Associated Papers
Mono and biallelic variants in HCN2 cause severe neurodevelopmental disorders.
Houdayer C et al.
Medrxiv : the Preprint Server for Health Sciences, 2024
A novel de novo HCN2 loss-of-function variant causing developmental and epileptic encephalopathy treated with a ketogenic diet.
DiFrancesco JC et al.
Epilepsia, 2023
The Contribution of HCN Channelopathies in Different Epileptic Syndromes, Mechanisms, Modulators, and Potential Treatment Targets: A Systematic Review.
Kessi M et al.
Frontiers in Molecular Neuroscience, 2022
Mutants of the Zebrafish K+ Channel Hcn2b Exhibit Epileptic-like Behaviors.
Rodríguez-Ortiz R et al.
International Journal of Molecular Sciences, 2021
Cardiac and neuronal HCN channelopathies.
Rivolta I et al.
Pflugers Archiv : European Journal of Physiology, 2020
Effects of HCN2 Mutations on Dendritic Excitability and Synaptic Plasticity: A Computational Study.
Thomas M et al.
Neuroscience, 2019
HCN ion channels and accessory proteins in epilepsy: genetic analysis of a large cohort of patients and review of the literature.
DiFrancesco JC et al.
Epilepsy Research, 2019
A novel de novo HCN1 loss-of-function mutation in genetic generalized epilepsy causing increased neuronal excitability.
Bonzanni M et al.
Neurobiology of Disease, 2018
The genetics and molecular biology of fever-associated seizures or epilepsy.
Deng H et al.
Expert Reviews in Molecular Medicine, 2018
Gain-of-function HCN2 variants in genetic epilepsy.
Li M et al.
Human Mutation, 2018
Ion Channel Genes and Epilepsy: Functional Alteration, Pathogenic Potential, and Mechanism of Epilepsy.
Wei F et al.
Neuroscience Bulletin, 2017
Novel HCN2 mutation contributes to febrile seizures by shifting the channel's kinetics in a temperature-dependent manner.
Nakamura Y et al.
Plos One, 2013
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