Varaico: Literature-Extracted Genetic Variants

Gene:HCN2
Variant:p.S198T
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HCN2

NM_001194.4:p.S198T

Associated Papers

The Contribution of HCN Channelopathies in Different Epileptic Syndromes, Mechanisms, Modulators, and Potential Treatment Targets: A Systematic Review.

Kessi M et al.

Frontiers in Molecular Neuroscience, 2022

Binding and structural asymmetry governs ligand sensitivity in a cyclic nucleotide-gated ion channel.

Ng LCT et al.

The Journal of General Physiology, 2019

The cGMP-dependent protein kinase II Is an inhibitory modulator of the hyperpolarization-activated HCN2 channel.

Hammelmann V et al.

Plos One, 2011

Gating of HCN channels by cyclic nucleotides: residue contacts that underlie ligand binding, selectivity, and efficacy.

Zhou L et al.

Structure (london, England : 1993), 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."