Varaico: Literature-Extracted Genetic Variants

Gene:HCN4
Variant:p.Y554F
Back to variants list

HCN4

NM_005477.3:p.Y554F

Associated Papers

The HCN4 channel mutation D553N associated with bradycardia has a C-linker mediated gating defect.

Netter MF et al.

Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 2012

Src tyrosine kinase alters gating of hyperpolarization-activated HCN4 pacemaker channel through Tyr531.

Li CH et al.

American Journal of Physiology. Cell Physiology, 2008

A novel mechanism of modulation of hyperpolarization-activated cyclic nucleotide-gated channels by Src kinase.

Zong X et al.

The Journal of Biological Chemistry, 2005

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."