Varaico: Literature-Extracted Genetic Variants

Gene:HDAC1
Variant:p.S423A
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HDAC1

NM_004964.3:p.S423A

Associated Papers

Multi-omics characterization of esophageal squamous cell carcinoma identifies molecular subtypes and therapeutic targets.

Zhao D et al.

Jci Insight, 2024

38652547 (PubMed )
Supplement: jciinsight-9-171916-s071.pdf

Molecular architecture of nucleosome remodeling and deacetylase sub-complexes by integrative structure determination.

Arvindekar S et al.

Protein Science : a Publication of the Protein Society, 2022

Histone deacetylase 1 phosphorylation at S421 and S423 is constitutive in vivo, but dispensable in vitro.

Karwowska-Desaulniers P et al.

Biochemical and Biophysical Research Communications, 2007

Histone deacetylase 1 phosphorylation promotes enzymatic activity and complex formation.

Pflum MK et al.

The Journal of Biological Chemistry, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."