Varaico: Literature-Extracted Genetic Variants

Gene:HDAC3
Variant:p.Y298H
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HDAC3

NM_003883.4:p.Y298H

Associated Papers

HDAC3 as an Emerging Therapeutic Target for Alzheimer's Disease and other Neurological Disorders.

Li Y et al.

Molecular Neurobiology, 2025

Enzyme-independent functions of HDAC3 in the adult heart.

Qian S et al.

Acta Pharmaceutica Sinica. B, 2025

Enzyme-independent functions of HDAC3 in the adult heart.

Qian S et al.

Biorxiv : the Preprint Server for Biology, 2024

De novo missense variants in HDAC3 leading to epigenetic machinery dysfunction are associated with a variable neurodevelopmental disorder.

Yoon JG et al.

American Journal of Human Genetics, 2024

Acetylation dependent translocation of EWSR1 regulates CHK2 alternative splicing in response to DNA damage.

Zhang T et al.

Oncogene, 2022

Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction.

Poleshko A et al.

Cell, 2017

Destabilization of Fatty Acid Synthase by Acetylation Inhibits De Novo Lipogenesis and Tumor Cell Growth.

Lin HP et al.

Cancer Research, 2016

Histone deacetylases: structural determinants of inhibitor selectivity.

Micelli C et al.

Drug Discovery Today, 2015

Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1.

Wang S et al.

Plos Biology, 2015

Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor.

Sun Z et al.

Molecular Cell, 2013

HDAC3 is a critical negative regulator of long-term memory formation.

McQuown SC et al.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."