Associated Papers
Lysine Deacetylase Substrate Selectivity: A Dynamic Ionic Interaction Specific to KDAC8.
Toro TB et al.
Biochemistry, 2021
Histone deacetylases: structural determinants of inhibitor selectivity.
Micelli C et al.
Drug Discovery Today, 2015
Histone deacetylase inhibitors suppress mutant p53 transcription via histone deacetylase 8.
Yan W et al.
Oncogene, 2013
HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle.
Deardorff MA et al.
Nature, 2012
Structural studies of human histone deacetylase 8 and its site-specific variants complexed with substrate and inhibitors.
Dowling DP et al.
Biochemistry, 2008
Structural and functional analysis of the human HDAC4 catalytic domain reveals a regulatory structural zinc-binding domain.
Bottomley MJ et al.
The Journal of Biological Chemistry, 2008
Substrate binding to histone deacetylases as shown by the crystal structure of the HDAC8-substrate complex.
Vannini A et al.
Embo Reports, 2007
Select a paper to view details