Associated Papers
HERC1 E3 Ubiquitin Ligase Is Necessary for Autophagy Processes and for the Maintenance and Homeostasis of Vesicles in Motor Nerve Terminals, but Not for Proteasomal Activity.
Pérez-Castro MÁ et al.
International Journal of Molecular Sciences, 2025
First Case of Macrocephaly, Dysmorphic Facies, and Psychomotor Retardation Harboring Co-inherited Variants in HERC1 and PMP22 Genes from Iran: Two Novel Variants.
Reshadmanesh A et al.
Archives of Iranian Medicine, 2024
Identification of a quality-control factor that monitors failures during proteasome assembly.
Zavodszky E et al.
Science (new York, N.y.), 2021
The HERC1 ubiquitin ligase regulates presynaptic membrane dynamics of central synapses.
Montes-Fernández MA et al.
Scientific Reports, 2020
HERC1 Ubiquitin Ligase Is Required for Hippocampal Learning and Memory.
Pérez-Villegas EM et al.
Frontiers in Neuroanatomy, 2020
HERCing: Structural and Functional Relevance of the Large HERC Ubiquitin Ligases.
García-Cano J et al.
Frontiers in Physiology, 2019
HERC1 Ubiquitin Ligase Is Required for Normal Axonal Myelination in the Peripheral Nervous System.
Bachiller S et al.
Molecular Neurobiology, 2018
The E3 ubiquitin ligase HERC1 controls the ERK signaling pathway targeting C-RAF for degradation.
Schneider T et al.
Oncotarget, 2018
Mutation of the HERC 1 Ubiquitin Ligase Impairs Associative Learning in the Lateral Amygdala.
Pérez-Villegas EM et al.
Molecular Neurobiology, 2018
A splice site mutation in HERC1 leads to syndromic intellectual disability with macrocephaly and facial dysmorphism: Further delineation of the phenotypic spectrum.
Aggarwal S et al.
American Journal of Medical Genetics. Part A, 2016
A nonsense variant in HERC1 is associated with intellectual disability, megalencephaly, thick corpus callosum and cerebellar atrophy.
Nguyen LS et al.
European Journal of Human Genetics : Ejhg, 2016
HERC 1 Ubiquitin Ligase Mutation Affects Neocortical, CA3 Hippocampal and Spinal Cord Projection Neurons: An Ultrastructural Study.
Ruiz R et al.
Frontiers in Neuroanatomy, 2016
Biallelic HERC1 mutations in a syndromic form of overgrowth and intellectual disability.
Ortega-Recalde O et al.
Clinical Genetics, 2015
The HERC1 E3 Ubiquitin Ligase is essential for normal development and for neurotransmission at the mouse neuromuscular junction.
Bachiller S et al.
Cellular and Molecular Life Sciences : Cmls, 2015
Progressive Purkinje cell degeneration in tambaleante mutant mice is a consequence of a missense mutation in HERC1 E3 ubiquitin ligase.
Mashimo T et al.
Plos Genetics, 2009