Varaico: Literature-Extracted Genetic Variants

Gene:HIF1A
Variant:p.A588T
Back to variants list

HIF1A

NM_001530.4:p.A588T

Associated Papers

A novel dual histone mark reader ZCWPW2 regulates meiotic recombination through lactylation and transcriptional regulation in humans and mice.

Ruan T et al.

Nucleic Acids Research, 2026

41574437 (PubMed )
Supplement: gkag049_supplemental_files.zip › Table_S6.xlsx › Table_S6

Role of genetic polymorphisms in residual ridge resorption of mandible - A scoping review.

Venkatesh SB et al.

The Japanese Dental Science Review, 2025

Genetic variability of HIF1A and response to treatment with cisplatin in combination with pemetrexed or gemcitabine in patients with malignant mesothelioma.

Setina M et al.

Radiology and Oncology, 2025

HFE-Related Hemochromatosis May Be a Primary Kupffer Cell Disease.

Kouroumalis E et al.

Biomedicines, 2025

Exploring the Correlation Between Hypoxia, HIF1A Variants, and Breast Cancer in Different Ethnicities, and Bangladeshi Women: Through ELISA and Integrative Multi-Omics Analysis.

Islam MS et al.

Biomarker Insights, 2024

Hypoxia-Inducible Pathway Polymorphisms and Their Role in the Complications of Prematurity.

Strauss E et al.

Genes, 2023

Genetic susceptibility of bladder cancer in the Lebanese population.

Kourie HR et al.

Bmc Medical Genomics, 2022

36253817 (PubMed )
Supplement: 12920_2022_1372_MOESM2_ESM.xlsx › Literature_review_table

Impact of germline polymorphisms in genes regulating glucose uptake on positron emission tomography findings and outcome in diffuse large B-cell lymphoma: results from the PETAL trial.

Broecker-Preuss M et al.

Journal of Cancer Research and Clinical Oncology, 2022

Association of hypoxia inducible factor 1-Alpha gene polymorphisms with multiple disease risks: A comprehensive meta-analysis.

Harun-Or-Roshid M et al.

Plos One, 2022

Association of rs11549465 (C1772T) variant of hypoxia-inducible factor-1α with Covid-19 susceptibility. A population-based epidemiological study.

Das A et al.

Human Cell, 2021

Integrative Map of HIF1A Regulatory Elements and Variations.

Kunej T

Genes, 2021

HIF1A polymorphisms do not modify the risk of epilepsy nor cerebral palsy after neonatal hypoxic-ischemic encephalopathy.

Kukec E et al.

Brain Research, 2021

HIF1A: A Putative Modifier of Hemochromatosis.

Pelucchi S et al.

International Journal of Molecular Sciences, 2021

Impact of Angiogenesis- and Hypoxia-Associated Polymorphisms on Tumor Recurrence in Patients with Hepatocellular Carcinoma Undergoing Surgical Resection.

Miller H et al.

Cancers, 2020

Genetic association of hypoxia inducible factor 1-alpha (HIF1A) Pro582Ser polymorphism with risk of diabetes and diabetic complications.

Ren H et al.

Aging, 2020

Stemness regulation of the adrenal mixed corticomedullary tumorigenesis-a case-control study.

Chiou HC et al.

Neoplasia (new York, N.y.), 2020

32438306 (PubMed )
Supplement: mmc1.pdf

Impact of the gene-gene interactions related to the HIF-1α signaling pathway with the knee osteoarthritis development.

Fernández-Torres J et al.

Clinical Rheumatology, 2019

Genetic variability of hypoxia-inducible factor alpha (HIFA) genes in familial erythrocytosis: Analysis of the literature and genome databases.

Kristan A et al.

European Journal of Haematology, 2019

Association of hypoxia-inducible factor-1α (HIF1α) 1790G/A gene polymorphism with renal cell carcinoma and prostate cancer susceptibility: a meta-analysis.

Li HY et al.

Bmc Medical Genetics, 2019

Clinicopathological characteristics and molecular abnormalities of primary grade 2 neuroendocrine tumors of the cervix.

Zhu R et al.

Diagnostic Pathology, 2019

The association of the placental Hypoxia-inducible factor1-α polymorphisms and HIF1-α mRNA expression with preeclampsia.

Harati-Sadegh M et al.

Placenta, 2018

Tumorigenicity-associated characteristics of human iPS cell lines.

Yasuda S et al.

Plos One, 2018

30286143 (PubMed )
Supplement: pone.0205022.s007.xlsx › Sheet1

Polymorphisms in oxidative pathway related genes and susceptibility to inflammatory bowel disease.

Senhaji N et al.

World Journal of Gastroenterology, 2017

The association of genetic polymorphisms of hypoxia inducible factor-1 alpha and vascular endothelial growth factor with increased risk of chronic obstructive pulmonary disease: A case-control study.

Yu ZG et al.

The Kaohsiung Journal of Medical Sciences, 2017

Genetic predisposition to lung cancer: comprehensive literature integration, meta-analysis, and multiple evidence assessment of candidate-gene association studies.

Wang J et al.

Scientific Reports, 2017

28827732 (PubMed )
Supplement: 41598_2017_7737_MOESM1_ESM.pdf

HIF1A gene polymorphisms and human diseases: Graphical review of 97 association studies.

Gladek I et al.

Genes, Chromosomes & Cancer, 2017

HIF1A (rs11549465) and AKNA (rs10817595) Gene Polymorphisms Are Associated with Primary Sjögren's Syndrome.

Hernández-Molina G et al.

Biomed Research International, 2017

Associations between HIF-1α polymorphisms C1772T and G1790A and susceptibility to chronic obstructive pulmonary disease.

Wei WT et al.

Genetics and Molecular Research : Gmr, 2015

Polymorphic variation of hypoxia inducible factor-1 A (HIF1A) gene might contribute to the development of knee osteoarthritis: a pilot study.

Fernández-Torres J et al.

Bmc Musculoskeletal Disorders, 2015

Impact of VEGF, VEGFR, PDGFR, HIF and ERCC1 gene polymorphisms on thymic malignancies outcome after thymectomy.

Berardi R et al.

Oncotarget, 2015

Polymorphisms of genes involved in the hypoxia signaling pathway and the development of abdominal aortic aneurysms or large-artery atherosclerosis.

Strauss E et al.

Journal of Vascular Surgery, 2015

The association between the rs11549465 polymorphism in the hif-1α gene and cancer risk: a meta-analysis.

Li Y et al.

International Journal of Clinical and Experimental Medicine, 2015

A meta-analysis of hypoxia inducible factor 1-alpha (HIF1A) gene polymorphisms: association with cancers.

Anam MT et al.

Biomarker Research, 2015

Genetic polymorphisms in hypoxia-inducible factor-1a gene and its association with HBV-related hepatocellular carcinoma in a Chinese population.

Liu Y et al.

Medical Oncology (northwood, London, England), 2014

HIF-1α genetic variants and protein expression confer the susceptibility and prognosis of gliomas.

Yi L et al.

Neuromolecular Medicine, 2014

Polymorphisms of HIF1A gene are associated with prognosis of early stage non-small-cell lung cancer patients after surgery.

Liu B et al.

Medical Oncology (northwood, London, England), 2014

HIF-1α P582S and A588T polymorphisms and digestive system cancer risk-a meta-analysis.

Yang X et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2014

HIF-1α polymorphism in the susceptibility of cervical spondylotic myelopathy and its outcome after anterior cervical corpectomy and fusion treatment.

Wang ZC et al.

Plos One, 2014

No association of hypoxia inducible factor-1α gene polymorphisms with breast cancer in North-West Indians.

Sharma S et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2014

1790 G/A polymorphism, but not 1772 C/T polymorphism, is significantly associated with cancers: an update study.

Liu J et al.

Gene, 2013

Lack of relevance of HIF-1α polymorphisms in breast cancer in a Portuguese population.

Ribeiro AL et al.

Anticancer Research, 2013

Single-nucleotide polymorphisms associated with outcome in metastatic renal cell carcinoma treated with sunitinib.

Beuselinck B et al.

British Journal of Cancer, 2013

Association between HIF1A P582S and A588T polymorphisms and the risk of urinary cancers: a meta-analysis.

Li D et al.

Plos One, 2013

Polymorphism in the hypoxia-inducible factor 1alpha gene may confer susceptibility to LDD in Chinese cohort.

Lin WP et al.

Plos One, 2013

An association study between hypoxia inducible factor-1alpha (HIF-1α) polymorphisms and osteonecrosis.

Chachami G et al.

Plos One, 2013

HIF1α genetic variants and protein expressions determine the response to platinum based chemotherapy and clinical outcome in patients with advanced NSCLC.

Wu F et al.

Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 2013

Common polymorphisms in angiogenesis.

Rogers MS et al.

Cold Spring Harbor Perspectives in Medicine, 2012

Ultrasound molecular imaging of angiogenesis induced by mutant forms of hypoxia-inducible factor-1α.

Xie J et al.

Cardiovascular Research, 2011

1–50 of 87 papers
Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."