Varaico: Literature-Extracted Genetic Variants

Gene:HIF1A
Variant:p.S597N
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HIF1A

NM_001530.4:p.S597N

Associated Papers

Role of genetic polymorphisms in residual ridge resorption of mandible - A scoping review.

Venkatesh SB et al.

The Japanese Dental Science Review, 2025

Interaction Between Hypoxia-Inducible Factor 1-alpha Gene Polymorphism and Helicobacter pylori Infection on Gastric Cancer in a Chinese Tibetan Population.

Li SH et al.

Biochemical Genetics, 2025

dbGVOSCC: a comprehensive database of genetic variation for systems genetics research on oral squamous cell carcinoma.

Zhou Y et al.

Frontiers in Oncology, 2025

41244916 (PubMed )
Supplement: DataSheet1.docx

Hypoxia-induced Factor-1α and its Role in Endometrial Cancer.

Smolarz B et al.

Anticancer Research, 2024

Impact of Long Noncoding RNA LINC00673 Genetic Variants on Susceptibility to Diabetic Retinopathy.

Chuang CC et al.

Frontiers in Genetics, 2022

Association of hypoxia inducible factor 1-Alpha gene polymorphisms with multiple disease risks: A comprehensive meta-analysis.

Harun-Or-Roshid M et al.

Plos One, 2022

Association of rs11549465 (C1772T) variant of hypoxia-inducible factor-1α with Covid-19 susceptibility. A population-based epidemiological study.

Das A et al.

Human Cell, 2021

In silico pathway analysis based on chromosomal instability in breast cancer patients.

Kour A et al.

Bmc Medical Genomics, 2020

Genetics of Degenerative Cervical Myelopathy: A Systematic Review and Meta-Analysis of Candidate Gene Studies.

Pope DH et al.

Journal of Clinical Medicine, 2020

Genetic variability of hypoxia-inducible factor alpha (HIFA) genes in familial erythrocytosis: Analysis of the literature and genome databases.

Kristan A et al.

European Journal of Haematology, 2019

Association of hypoxia-inducible factor-1α (HIF1α) 1790G/A gene polymorphism with renal cell carcinoma and prostate cancer susceptibility: a meta-analysis.

Li HY et al.

Bmc Medical Genetics, 2019

A Genetic Association Study of a Specific Gene and Severe Form of Resorption in the Edentulous Mandible in the Egyptian Population.

Emam SM et al.

Journal of Prosthodontics : Official Journal of the American College of Prosthodontists, 2019

Association of hypoxia-inducible factor-1 alpha gene polymorphism with renal cell carcinoma susceptibility.

Huang L et al.

Journal of Cancer Research and Therapeutics, 2018

The association of the placental Hypoxia-inducible factor1-α polymorphisms and HIF1-α mRNA expression with preeclampsia.

Harati-Sadegh M et al.

Placenta, 2018

Investigation of GLUT1, HIF1α and TBX21 Gene Polymorphisms in Laryngeal Cancer.

Uslu C et al.

Turkish Archives of Otorhinolaryngology, 2018

HIF1A gene rs10873142 polymorphism is associated with risk of chronic obstructive pulmonary disease in a Chinese Han population: a case-control study.

Wang L et al.

Bioscience Reports, 2018

Hypoxia-inducible factor-1α rs11549465 C>T and rs11549467 G>A gene polymorphisms are associated with an increased risk of digestive cancers in Asians.

Wang W et al.

Journal of Cancer Research and Therapeutics, 2018

The association of genetic polymorphisms of hypoxia inducible factor-1 alpha and vascular endothelial growth factor with increased risk of chronic obstructive pulmonary disease: A case-control study.

Yu ZG et al.

The Kaohsiung Journal of Medical Sciences, 2017

Association of breast cancer risk and the mTOR pathway in women of African ancestry in 'The Root' Consortium.

Wang S et al.

Carcinogenesis, 2017

Association between genetic polymorphisms involved in the hypoxia-inducible factor pathway and lung cancer risk: a case-control study in Japan.

Yamamoto Y et al.

Asia-pacific Journal of Clinical Oncology, 2017

HIF1A gene polymorphisms and human diseases: Graphical review of 97 association studies.

Gladek I et al.

Genes, Chromosomes & Cancer, 2017

Sequence and functional characterization of hypoxia-inducible factors, HIF1α, HIF2αa, and HIF3α, from the estuarine fish, Fundulus heteroclitus.

Townley IK et al.

American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 2017

Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity.

Choudhury Y et al.

Scientific Reports, 2017

28120901 (PubMed )
Supplement: srep41238-s1.pdf

Associations between HIF-1α polymorphisms C1772T and G1790A and susceptibility to chronic obstructive pulmonary disease.

Wei WT et al.

Genetics and Molecular Research : Gmr, 2015

Polymorphic variation of hypoxia inducible factor-1 A (HIF1A) gene might contribute to the development of knee osteoarthritis: a pilot study.

Fernández-Torres J et al.

Bmc Musculoskeletal Disorders, 2015

SNP rs2057482 in HIF1A gene predicts clinical outcome of aggressive hepatocellular carcinoma patients after surgery.

Guo X et al.

Scientific Reports, 2015

Polymorphisms of genes involved in the hypoxia signaling pathway and the development of abdominal aortic aneurysms or large-artery atherosclerosis.

Strauss E et al.

Journal of Vascular Surgery, 2015

HIF-1α (1772C>T) polymorphism as marker for breast cancer development.

Meka PB et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2015

Association between the polymorphisms of the vascular endothelial growth factor gene and metabolic syndrome.

Kim YR et al.

Biomedical Reports, 2015

HIF-1α -1790G>A polymorphism significantly increases the risk of digestive tract cancer: a meta-analysis.

Sun X et al.

World Journal of Gastroenterology, 2015

The association between the rs11549465 polymorphism in the hif-1α gene and cancer risk: a meta-analysis.

Li Y et al.

International Journal of Clinical and Experimental Medicine, 2015

Potential signaling pathway of hypoxia-inducible factor in lung cancer and its gene polymorphism with lung cancer risk.

Liao SH et al.

Journal of Receptor and Signal Transduction Research, 2015

A meta-analysis of hypoxia inducible factor 1-alpha (HIF1A) gene polymorphisms: association with cancers.

Anam MT et al.

Biomarker Research, 2015

Genetic polymorphisms in hypoxia-inducible factor-1a gene and its association with HBV-related hepatocellular carcinoma in a Chinese population.

Liu Y et al.

Medical Oncology (northwood, London, England), 2014

HIF-1α genetic variants and protein expression confer the susceptibility and prognosis of gliomas.

Yi L et al.

Neuromolecular Medicine, 2014

Common polymorphisms in the HIF-1α gene confer susceptibility to digestive cancer: a meta-analysis.

Xu JJ et al.

Genetics and Molecular Research : Gmr, 2014

The HIF1A rs2057482 polymorphism is associated with risk of developing premature coronary artery disease and with some metabolic and cardiovascular risk factors. The Genetics of Atherosclerotic Disease (GEA) Mexican Study.

López-Reyes A et al.

Experimental and Molecular Pathology, 2014

Hypoxia-inducible factor-1α (HIF-1α) C1772T polymorphism significantly contributes to the risk of malignancy from a meta-analysis.

Wu G et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2014

Hypoxia-inducible factor-1α C1772T polymorphism and cancer risk: a meta-analysis including 18,334 subjects.

Ye Y et al.

Cancer Investigation, 2014

HIF-1α P582S and A588T polymorphisms and digestive system cancer risk-a meta-analysis.

Yang X et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2014

The association between hypoxia-inducible factor-1 α gene G1790A polymorphism and cancer risk: a meta-analysis of 28 case-control studies.

Zhou Y et al.

Cancer Cell International, 2014

Genetic variations in the HIF1A gene modulate response to adjuvant chemotherapy after surgery in patients with colorectal cancer.

Zhang Y et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2014

HIF-1α polymorphism in the susceptibility of cervical spondylotic myelopathy and its outcome after anterior cervical corpectomy and fusion treatment.

Wang ZC et al.

Plos One, 2014

No association of hypoxia inducible factor-1α gene polymorphisms with breast cancer in North-West Indians.

Sharma S et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2014

High HIF-1α expression genotypes in oral lichen planus.

de Carvalho Fraga CA et al.

Clinical Oral Investigations, 2013

Clinicopathological significance of hypoxia-inducible factor-1 alpha polymorphisms in cancers: evidence from a meta-analysis.

Hu X et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."