Varaico: Literature-Extracted Genetic Variants

Gene:HIPK2
Variant:p.Y361F
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HIPK2

NM_022740.5:p.Y361F

Associated Papers

The crystal structure of the protein kinase HIPK2 reveals a unique architecture of its CMGC-insert region.

Agnew C et al.

The Journal of Biological Chemistry, 2019

Effects of Y361-auto-phosphorylation on structural plasticity of the HIPK2 kinase domain.

Scaglione A et al.

Protein Science : a Publication of the Protein Society, 2018

HIPK2-T566 autophosphorylation diversely contributes to UV- and doxorubicin-induced HIPK2 activation.

Verdina A et al.

Oncotarget, 2017

Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis.

Lee S et al.

Neuron, 2016

Effect of tyrosine autophosphorylation on catalytic activity and subcellular localisation of homeodomain-interacting protein kinases (HIPK).

van der Laden J et al.

Cell Communication and Signaling : Ccs, 2015

Transcriptional corepressors HIPK1 and HIPK2 control angiogenesis via TGF-β-TAK1-dependent mechanism.

Shang Y et al.

Plos Biology, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."