Varaico: Literature-Extracted Genetic Variants

Gene:HLA-B
Variant:p.R103Q
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HLA-B

NM_005514.8:p.R103Q

Associated Papers

Impact of tumor necrosis factor-alpha gene variant in pediatric nephrotic syndrome: a meta-analysis.

Venkatachalapathy Y et al.

Scientific Reports, 2025

Tumor Necrosis Factor-Alpha (+489 G/A) Polymorphism Can Predict the Response to Adalimumab in Chinese Han Patients With Ankylosing Spondylitis.

Liang HJ et al.

Cureus, 2023

Estimating the role of single-nucleotide polymorphism (rs1800629)-308 G/A of TNF-alpha gene as genetic marker associated with angina pectoris in a sample of Iraqi patients.

Abdulfattah SY et al.

Journal, Genetic Engineering & Biotechnology, 2023

Does TNF-α 308 G/A (rs1800629) gene polymorphism associate with liver and pancreas disorders in Iraqi adults with beta thalassemia major?

Luaibi HA et al.

Human Antibodies, 2023

The synergistic role of TNFA - 308G/A and IL10 - 1082A/G polymorphisms in ankylosing spondylitis.

Ivanova M et al.

Rheumatology International, 2021

Association of TNF-α-308 G>A (rs1800629) polymorphism with susceptibility of metabolic syndrome.

Ghareeb D et al.

Journal of Diabetes and Metabolic Disorders, 2021

Tumor Necrosis Factor Alpha -308G/A Gene Polymorphisms Combined with Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratio Predicts the Efficacy and Safety of Anti-TNF-α Therapy in Patients with Ankylosing Spondylitis, Rheumatoid Arthritis, and Psoriasis Arthritis.

Wang Z et al.

Frontiers in Pharmacology, 2021

Associations of the -238(G/A) and -308(G/A) TNF-α Promoter Polymorphisms and TNF-α Serum Levels with the Susceptibility to Gastric Precancerous Lesions and Gastric Cancer Related to Helicobacter pylori Infection in a Moroccan Population.

Bounder G et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2020

Tumor Necrosis Factor-α Gene Polymorphism (G-308A) and Dilated Cardiomyopathy.

Chen M et al.

International Heart Journal, 2019

Association between cytokine gene polymorphisms and ankylosing spondylitis susceptibility: a systematic review and meta-analysis.

Xia Y et al.

Postgraduate Medical Journal, 2018

Association between cytokine genes polymorphisms and type 1 diabetes: a case-control study on Saudi population.

Allam G et al.

Immunological Investigations, 2018

Genetics in TNF-TNFR pathway: A complex network causing spondyloarthritis and conditioning response to anti-TNFα therapy.

Aita A et al.

Plos One, 2018

Importance of polymorphic variants of Tumour Necrosis Factor - α gene in the etiology of Intrauterine Growth Restriction.

Kaluba-Skotarczak A et al.

Ginekologia Polska, 2018

Function of tumor necrosis factor alpha before and after mutation in gastric cancer.

Zhang X et al.

Saudi Journal of Biological Sciences, 2017

Association between TNFA Gene Polymorphisms and Helicobacter pylori Infection: A Meta-Analysis.

Sun X et al.

Plos One, 2016

TNF-308 G/A polymorphism and risk of systemic lupus erythematosus in the Polish population.

Piotrowski P et al.

Modern Rheumatology, 2015

Inflammation-related cytokine gene polymorphisms in Behçet's disease.

Al-Okaily F et al.

Journal of Inflammation Research, 2015

Association of single nucleotide polymorphism at position -308 of the tumor necrosis factor-alpha gene with ankylosing spondylitis and rheumatoid arthritis.

Manolova I et al.

Biotechnology, Biotechnological Equipment, 2014

TNF-308 G/A polymorphism and risk of acne vulgaris: a meta-analysis.

Yang JK et al.

Plos One, 2014

The association between tumor necrosis factor alpha promoter polymorphisms and ankylosing spondylitis: a meta-analysis.

Ma B et al.

Human Immunology, 2013

[Tumor necrosis factor alpha-238G/A polymorphism and tuberculosis susceptibility: a meta-analysis].

Zhang ZJ et al.

Zhonghua Jie He He Hu Xi Za Zhi = Zhonghua Jiehe He Huxi Zazhi = Chinese Journal of Tuberculosis and Respiratory Diseases, 2013

Tumor necrosis factor-α 238 G/A polymorphism and risk of hepatocellular carcinoma: evidence from a meta-analysis.

Cheng K et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2013

TNF-α -857C>T genotype is predictive of clinical response after treatment with definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma.

Omatsu H et al.

International Journal of Medical Sciences, 2013

Association of TNF-α and Fas gene promoter polymorphism with the risk of Kashin-Beck disease in Northwest Chinese population.

Zhao QM et al.

Clinical Rheumatology, 2012

TNF-α promoter polymorphism: a factor contributing to the different immunological and clinical phenotypes in Japanese encephalitis.

Pujhari SK et al.

Bmc Infectious Diseases, 2012

Relation of HLA-B27, tumor necrosis factor-α promoter gene polymorphisms, and T cell cytokine production in ankylosing spondylitis -- a comprehensive genotype-phenotype analysis from an observational cohort.

Poddubnyy DA et al.

The Journal of Rheumatology, 2011

Polymorphisms of tumor necrosis factor-α promoter region for susceptibility to HLA-B27-positive ankylosing spondylitis in Korean population.

Chung WT et al.

Rheumatology International, 2011

The TNF-α, IL-1B and IL-10 polymorphisms and risk for hepatocellular carcinoma: a meta-analysis.

Yang Y et al.

Journal of Cancer Research and Clinical Oncology, 2011

A pilot study of the association of tumor necrosis factor alpha polymorphisms with psoriatic arthritis in the Romanian population.

Popa OM et al.

International Journal of Molecular Sciences, 2011

TNF-alpha gene polymorphisms in Iranian Azeri Turkish patients with Behcet's Disease.

Bonyadi M et al.

Rheumatology International, 2009

Tumor necrosis factor region polymorphisms are associated with AIDS and with cytomegalovirus retinitis.

Deghaide NH et al.

Aids (london, England), 2009

Role of non-HLA genetic variants in end-stage renal disease.

Ranganath P et al.

Tissue Antigens, 2009

Tumor necrosis factor alpha -308 gene locus promoter polymorphism: an analysis of association with health and disease.

Elahi MM et al.

Biochimica Et Biophysica Acta, 2009

Higher LPS-stimulated TNF-alpha mRNA levels in peripheral blood mononuclear cells from Chinese ankylosing spondylitis patients with -308G/A polymorphism in promoter region of tumor necrosis factor: association with distinct A33/B58/Cw10 haplotypes.

Lu MC et al.

Rheumatology International, 2008

Single nucleotide polymorphism in the tumor necrosis factor-alpha gene affects inflammatory bowel diseases risk.

Ferguson LR et al.

World Journal of Gastroenterology, 2008

Association of TNF polymorphisms with sarcoidosis, its prognosis and tumour necrosis factor (TNF)-alpha levels in Asian Indians.

Sharma S et al.

Clinical and Experimental Immunology, 2008

Pharmacogenetic determinants of immediate and delayed reactions of drug hypersensitivity.

Guéant JL et al.

Current Pharmaceutical Design, 2008

TNF-alpha gene promoter -238G>A and -308G>A polymorphisms alter risk of psoriasis vulgaris: a meta-analysis.

Li C et al.

The Journal of Investigative Dermatology, 2007

Lack of association of tumor necrosis factor-alpha gene polymorphisms with disease susceptibility and severity in Behçet's disease.

Ateş A et al.

Rheumatology International, 2006

Tumour necrosis factor-alpha promoter polymorphism and its association with viral dilated cardiomyopathy in Indian population: a pilot study.

Mishra B et al.

Indian Journal of Medical Microbiology, 0

A meta-analysis for association of TNF-α -308G>A polymorphism with susceptibility to Ankylosing Spondylitis.

Mahdinejad-Yazdi M et al.

Journal of Orthopaedics, 0

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