Varaico: Literature-Extracted Genetic Variants

Gene:HLTF
Variant:p.E259K
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HLTF

NM_003071.4:p.E259K

Associated Papers

CPX-351 induces remission in newly diagnosed pediatric secondary myeloid malignancies.

Hu Y et al.

Blood Advances, 2022

34710216 (PubMed )
Supplement: advancesADV2021006139-suppl1.pdf

New progress in the study of germline susceptibility genes of myeloid neoplasms.

Bi L et al.

Oncology Letters, 2021

A germline HLTF mutation in familial MDS induces DNA damage accumulation through impaired PCNA polyubiquitination.

Takaoka K et al.

Leukemia, 2019

Post-replication repair: Rad5/HLTF regulation, activity on undamaged templates, and relationship to cancer.

Gallo D et al.

Critical Reviews in Biochemistry and Molecular Biology, 2019

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."