Associated Papers
Cholesterol sulfate as a negative regulator of cellular cholesterol homeostasis.
Nam LB et al.
Molecules and Cells, 2025
Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain.
Chen H et al.
Nature Communications, 2022
Enhanced ER-associated degradation of HMG CoA reductase causes embryonic lethality associated with Ubiad1 deficiency.
Jo Y et al.
Elife, 2020
Schnyder corneal dystrophy-associated UBIAD1 inhibits ER-associated degradation of HMG CoA reductase in mice.
Jo Y et al.
Elife, 2019
Isolation of mutant cells lacking Insig-1 through selection with SR-12813, an agent that stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Sever N et al.
The Journal of Biological Chemistry, 2004
Ubiquitin is conjugated by membrane ubiquitin ligase to three sites, including the N terminus, in transmembrane region of mammalian 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for sterol-regulated enzyme degradation.
Doolman R et al.
The Journal of Biological Chemistry, 2004
Select a paper to view details