Associated Papers
Bridging pancreatic and hepatic development: overlapping genes and their role in diabetes.
Ghanem SS et al.
Cellular & Molecular Biology Letters, 2025
HNF4A and HNF1A exhibit tissue specific target gene regulation in pancreatic beta cells and hepatocytes.
Ng NHJ et al.
Nature Communications, 2024
Identification and precision therapy for three maturity-onset diabetes of the young (MODY) families caused by mutations in the HNF4A gene.
Zhang J et al.
Frontiers in Endocrinology, 2023
Toward Precision Medicine with Human Pluripotent Stem Cells for Diabetes.
Memon B et al.
Stem Cells Translational Medicine, 2022
Spatial Environment Affects HNF4A Mutation-Specific Proteome Signatures and Cellular Morphology in hiPSC-Derived β-Like Cells.
Carrasco M et al.
Diabetes, 2022
The application of precision medicine in monogenic diabetes.
Barbetti F et al.
Expert Review of Endocrinology & Metabolism, 2022
Stem Cell-Derived β Cells: A Versatile Research Platform to Interrogate the Genetic Basis of β Cell Dysfunction.
Bartolomé A
International Journal of Molecular Sciences, 2022
Modeling Maturity Onset Diabetes of the Young in Pluripotent Stem Cells: Challenges and Achievements.
Braverman-Gross C et al.
Frontiers in Endocrinology, 2021
Bioinformatic Analyses of miRNA-mRNA Signature during hiPSC Differentiation towards Insulin-Producing Cells upon HNF4α Mutation.
Ghila L et al.
Biomedicines, 2020
HNF4A Haploinsufficiency in MODY1 Abrogates Liver and Pancreas Differentiation from Patient-Derived Induced Pluripotent Stem Cells.
Ng NHJ et al.
Iscience, 2019
Probing the missing mature β-cell proteomic landscape in differentiating patient iPSC-derived cells.
Vethe H et al.
Scientific Reports, 2017
Derivation of human induced pluripotent stem cells from patients with maturity onset diabetes of the young.
Teo AK et al.
The Journal of Biological Chemistry, 2013
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