Varaico: Literature-Extracted Genetic Variants

Gene:HOXB13
Variant:p.*285K
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HOXB13

NM_006361.6:p.*285K

Associated Papers

NCCN Guidelines® Insights: Genetic/Familial High-Risk Assessment: Breast, Ovarian, Pancreatic, and Prostate, Version 2.2026.

Cheng HH et al.

Journal of the National Comprehensive Cancer Network : Jnccn, 2026

Germline DNA Repair and Immune-metabolic Alterations Suggest a Potentially Distinct Form of Early-onset Prostate Cancer in Men of African Descent.

Loger JS et al.

European Urology Oncology, 2025

Prevalence and clinical significance of the rare HOXB13 X285K variant in a French Caribbean prostate cancer cohort.

Rose-Dite-Modestine J et al.

Bmc Cancer, 2025

Germline Testing for Prostate Cancer Patients: Evidence-Based Evaluation of Genes Recommended by NCCN Guidelines.

Xu J et al.

The Prostate, 2025

Prostate cancer and genetic contributions.

Chou WH et al.

Andrology, 2025

Case series exploring hormonal sensitivity in prostate cancer patients harboring the germline African-ancestry HOXB13 X285K variant.

Kanayama M et al.

Prostate Cancer and Prostatic Diseases, 2025

Rare pathogenic structural variants show potential to enhance prostate cancer germline testing for African men.

Gong T et al.

Nature Communications, 2025

Ancestry-Specific DNA Damage Repair Gene Mutations and Prostate Cancer.

Borbiev T et al.

Cancers, 2025

Delineating the roles of HOXB13 X285K variant in prostate cancer.

Lu X et al.

Serican Journal of Medicine, 2025

Evaluation of homeobox protein B13 (HOXB13) gene G84E mutation in patients with prostate cancer.

Bıyıkoğlu M et al.

World Journal of Urology, 2024

Clinical and Functional Analyses of an African-ancestry Gain-of-function HOXB13 Variant Implicated in Aggressive Prostate Cancer.

Kanayama M et al.

European Urology Oncology, 2024

Rare pathogenic structural variants show potential to enhance prostate cancer germline testing for African men.

Hayes V et al.

Research Square, 2024

Prostate cancer genetic risk and associated aggressive disease in men of African ancestry.

Soh PXY et al.

Nature Communications, 2023

Aligning germline and somatic mutations in prostate cancer. Are genetics changing practice?

Cussenot O et al.

Bju International, 2023

Clinicopathological Characteristics and Mutational Landscape of APC, HOXB13, and KRAS among Rwandan Patients with Colorectal Cancer.

Manirakiza F et al.

Current Issues in Molecular Biology, 2023

Germline Variants in DNA Damage Repair Genes and HOXB13 Among Black Patients With Early-Onset Prostate Cancer.

Trendowski MR et al.

Jco Precision Oncology, 2022

The role of genetic testing in prostate cancer screening, diagnosis, and treatment.

de la Calle CM et al.

Current Opinion in Oncology, 2022

A Rare Germline HOXB13 Variant Contributes to Risk of Prostate Cancer in Men of African Ancestry.

Darst BF et al.

European Urology, 2022

The HOXB13 variant X285K is associated with clinical significance and early age at diagnosis in African American prostate cancer patients.

Na R et al.

British Journal of Cancer, 2022

Hereditary variants of unknown significance in African American women with breast cancer.

McDonald JT et al.

Plos One, 2022

36315513 (PubMed )
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