Varaico: Literature-Extracted Genetic Variants

Gene:HOXB13
Variant:p.R217C
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HOXB13

NM_006361.6:p.R217C

Associated Papers

The evolutionary impact of childhood cancer on the human gene pool.

Stoltze UK et al.

Nature Communications, 2024

38424437 (PubMed )
Supplement: 41467_2024_45975_MOESM4_ESM.xlsx › Supplementary_Data_15

Comprehensive germline-genomic and clinical profiling in 160 unselected children and adolescents with cancer.

Wagener R et al.

European Journal of Human Genetics : Ejhg, 2021

33840814 (PubMed )
Supplement: 41431_2021_878_MOESM2_ESM.xlsx › Table_S3

Divergent Roles of PI3K Isoforms in PTEN-Deficient Glioblastomas.

Xie S et al.

Cell Reports, 2020

32997991 (PubMed )
Supplement: NIHMS1633676-supplement-2.xlsx › BT224_Mutations

Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk.

Liu J et al.

Scientific Reports, 2020

In silico analysis of the deleterious nsSNPs (missense) in the homeobox domain of human HOXB13 gene responsible for hereditary prostate cancer.

Chandrasekaran G et al.

Chemical Biology & Drug Design, 2017

HOXB13 mutations and binding partners in prostate development and cancer: Function, clinical significance, and future directions.

Brechka H et al.

Genes & Diseases, 2017

Computational Modeling of complete HOXB13 protein for predicting the functional effect of SNPs and the associated role in hereditary prostate cancer.

Chandrasekaran G et al.

Scientific Reports, 2017

28272408 (PubMed )
Supplement: srep43830-s1.zip › SR_Supplementary_Data_Files_Complete › PROVEAN › PROVEAN_results.pdf

Recurrent HOXB13 mutations in the Dutch population do not associate with increased breast cancer risk.

Liu J et al.

Scientific Reports, 2016

Identification of Two Novel HOXB13 Germline Mutations in Portuguese Prostate Cancer Patients.

Maia S et al.

Plos One, 2015

A population-based assessment of germline HOXB13 G84E mutation and prostate cancer risk.

Karlsson R et al.

European Urology, 2014

Genome-wide testing of putative functional exonic variants in relationship with breast and prostate cancer risk in a multiethnic population.

Haiman CA et al.

Plos Genetics, 2013

23555315 (PubMed )
Supplement: pgen.1003419.s009.xlsx › Sheet1

HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG).

Xu J et al.

Human Genetics, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."