Associated Papers
NCCN Guidelines® Insights: Genetic/Familial High-Risk Assessment: Breast, Ovarian, Pancreatic, and Prostate, Version 2.2026.
Cheng HH et al.
Journal of the National Comprehensive Cancer Network : Jnccn, 2026
The castration-resistant prostate cancer-associated SNP rs11067228 facilitates neuroendocrine differentiation through an enhancer-mediated chromatin interaction with SRRM4.
Jiang Y et al.
International Journal of Biological Sciences, 2026
Precision Care for Hereditary Urologic Cancers: Genetic Testing, Counseling, Surveillance, and Therapeutic Implications.
Somoto T et al.
Current Oncology (toronto, Ont.), 2025
The Concordance of Secondary Pathogenic Germline Variants Identified by Tumor Genomic Profiling in Adult Solid Tumor Patients at Two US Community Cancer Centers.
Moncado S et al.
Genes, 2025
Prevalence of germline pathogenic variants in cancer predisposition genes in the Japanese population.
Yamaguchi T et al.
Japanese Journal of Clinical Oncology, 2025
High-Grade Early-Onset Prostate Cancer: Assessment of TMPRSS2::ERG -Negative Tumors Suggests Low Frequency of Germline Alterations and a Pathogenic Role for HOXB13.
Maharjan D et al.
The American Journal of Surgical Pathology, 2025
Confirmation of BIK and SAMHD1 as Prostate Cancer Susceptibility Genes.
Pavlovich CP et al.
The Prostate, 2025
Circulating Tumor DNA as a Biomarker for Precision Medicine in Prostate Cancer: A Systematic Review.
Chanhih N et al.
International Journal of Molecular Sciences, 2025
Prevalence and clinical significance of the rare HOXB13 X285K variant in a French Caribbean prostate cancer cohort.
Rose-Dite-Modestine J et al.
Bmc Cancer, 2025
Association of HOXB13 G84E With Prostate Cancer Among 592,158 Men.
Crawford TB et al.
Journal of the National Comprehensive Cancer Network : Jnccn, 2025
Generating a database by calculating the pathogenic variants and allele frequencies detected in hereditary cancers using genomic data: A nation study.
Ali MSB et al.
Global Medical Genetics, 2025
Germline Cancer Susceptibility Variants in Patients With Uveal Melanoma.
Repo PE et al.
Pigment Cell & Melanoma Research, 2025
Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy.
Liu J et al.
Nature Genetics, 2025
Pathogenic germline variants in small cell lung cancer: A systematic review and meta-analysis.
Ul Haq S et al.
Hgg Advances, 2025
Pan-Cancer Exome-wide analysis of germline mutational patterns and pathways.
Alnaqbi H et al.
Scientific Reports, 2025
Genetic determinants of prostate cancer predisposition in Ashkenazi Jews.
Perletti G et al.
Archivio Italiano Di Urologia, Andrologia : Organo Ufficiale [di] Societa Italiana Di Ecografia Urologica E Nefrologica, 2025
Case series exploring hormonal sensitivity in prostate cancer patients harboring the germline African-ancestry HOXB13 X285K variant.
Kanayama M et al.
Prostate Cancer and Prostatic Diseases, 2025
Impact of CHEK2 germline variants on haematological malignancy risk and outcomes of allogeneic HSCT.
Lahtinen AK et al.
British Journal of Haematology, 2025
Exome-based cancer predisposition gene testing can provide a genetic diagnosis for individuals with heterogeneous tumor phenotypes.
Hinić S et al.
European Journal of Human Genetics : Ejhg, 2025
Rare variants and survival of patients with idiopathic pulmonary fibrosis: analysis of a multicentre, observational cohort study with independent validation.
Alonso-González A et al.
The Lancet. Respiratory Medicine, 2025
VADEr: Vision Transformer-Inspired Framework for Polygenic Risk Reveals Underlying Genetic Heterogeneity in Prostate Cancer.
Talwar JV et al.
Medrxiv : the Preprint Server for Health Sciences, 2025
Assessing the contribution of rare protein-coding germline variants to prostate cancer risk and severity in 37,184 cases.
Mitchell J et al.
Nature Communications, 2025
Clinical integration of germline findings from a tumor testing precision medicine program.
Sanabria-Salas MC et al.
Bmc Cancer, 2025
Delineating the roles of HOXB13 X285K variant in prostate cancer.
Lu X et al.
Serican Journal of Medicine, 2025
A systematic review of family history, race/ethnicity, and genetic risk on prostate cancer detection and outcomes: Considerations in PSA-based screening.
Graham NJ et al.
Urologic Oncology, 2025
Germline genetic mutations in a multi-center cohort of 248 phyllodes tumors.
Rosenberger LH et al.
Breast Cancer Research and Treatment, 2025
Using Family History Data to Improve the Power of Association Studies: Application to Cancer in UK Biobank.
Wilcox N et al.
Genetic Epidemiology, 2025
Coding Variants of the Genitourinary Development Gene WNT9B Carry High Risk for Prostate Cancer.
Dupont WD et al.
Jco Precision Oncology, 2025
Significantly increased load of hereditary cancer-linked germline variants in infertile men.
Valkna A et al.
Human Reproduction Open, 2025
Integrating molecular diagnostics for early prostate cancer detection.
Umarane PB et al.
Oncoscience, 2025
Genetic and Non-Genetic Risk Factors in Prostate Cancer: Towards a Precision Medicine Approach.
Hloušek S et al.
Folia Biologica, 2025
Validation of the NovaSeq6000 platform and automated library preparation for CE-IVD equivalence.
Pasquinelli E et al.
Computational and Structural Biotechnology Journal, 2025
Predictive Genetic Testing in the Cancer Management and Prevention.
Najafi N et al.
Journal of Cancer Science and Clinical Therapeutics, 2025
Clinician-Reported Management Recommendations in Response to Universal Germline Genetic Testing in Patients With Prostate Cancer.
Shore N et al.
The Journal of Urology, 2024
Germline pathogenic variants in prostate cancer.
Shakroo YM et al.
Pathology, Research and Practice, 2024
Clinically Relevant Germline Variants in Children With Nonmedullary Thyroid Cancer.
van der Tuin K et al.
The Journal of Clinical Endocrinology and Metabolism, 2024
Multiple Myeloma Risk and Outcomes Are Associated with Pathogenic Germline Variants in DNA Repair Genes.
Thibaud S et al.
Blood Cancer Discovery, 2024
Rare variants and survival of patients with idiopathic pulmonary fibrosis.
Alonso-Gonzalez A et al.
Medrxiv : the Preprint Server for Health Sciences, 2024
Screening guidelines for individuals at increased risk for prostate cancer.
Lorentz J et al.
Canadian Urological Association Journal = Journal De L'association Des Urologues Du Canada, 2024
Prognostic value of germline mutations in metastatic hormone-sensitive prostate cancer (mHSPC).
Custodio-Cabello S et al.
Urologic Oncology, 2024
Study of HOXB13 Gene Variants in Prostate Cancer Patients.
Sulaiman KM et al.
Cureus, 2024
Evaluation of homeobox protein B13 (HOXB13) gene G84E mutation in patients with prostate cancer.
Bıyıkoğlu M et al.
World Journal of Urology, 2024