Varaico: Literature-Extracted Genetic Variants

Gene:HPF1
Variant:p.E284A
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HPF1

NM_017867.3:p.E284A

Associated Papers

Molecular basis of threonine ADP-ribosylation of ubiquitin by bacterial ARTs.

Tan J et al.

Nature Chemical Biology, 2024

HPF1-dependent histone ADP-ribosylation triggers chromatin relaxation to promote the recruitment of repair factors at sites of DNA damage.

Smith R et al.

Nature Structural & Molecular Biology, 2023

HPF1 remodels the active site of PARP1 to enable the serine ADP-ribosylation of histones.

Sun FH et al.

Nature Communications, 2021

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."