Varaico: Literature-Extracted Genetic Variants

Gene:HRAS
Variant:p.L133R
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HRAS

NM_005343.4:p.L133R

Associated Papers

Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy.

Holderfield M et al.

Nature, 2024

38589574 (PubMed )
Supplement: 41586_2024_7205_MOESM5_ESM.xlsx › Additional_Cell_Panel_Data

Structural bioinformatics enhances mechanistic interpretation of genomic variation, demonstrated through the analyses of 935 distinct RAS family mutations.

Tripathi S et al.

Bioinformatics (oxford, England), 2021

33226070 (PubMed )
Supplement: btaa972_supplementary_data.zip › RAS_Manuscript_RMarkdown.tar.gz › RAS_Manuscript1.Revised › RAS_Variants_Scores.xlsx › Sheet1

LowMACA: exploiting protein family analysis for the identification of rare driver mutations in cancer.

Melloni GE et al.

Bmc Bioinformatics, 2016

26860319 (PubMed )
Supplement: 12859_2016_935_MOESM2_ESM.xlsx › Table_S5

Exploiting high-throughput cell line drug screening studies to identify candidate therapeutic agents in head and neck cancer.

Nichols AC et al.

Bmc Pharmacology & Toxicology, 2014

25428177 (PubMed )
Supplement: 40360_2014_350_MOESM1_ESM.xlsx › Supp._Table_1
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."