Varaico: Literature-Extracted Genetic Variants

Gene:HRAS
Variant:p.K117E
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HRAS

NM_005343.4:p.K117E

Associated Papers

Beyond structural bioinformatics for genomics with dynamics characterization of an expanded KRAS mutational landscape.

Ratnasinghe BD et al.

Computational and Structural Biotechnology Journal, 2023

Structural bioinformatics enhances mechanistic interpretation of genomic variation, demonstrated through the analyses of 935 distinct RAS family mutations.

Tripathi S et al.

Bioinformatics (oxford, England), 2021

33226070 (PubMed )
Supplement: btaa972_supplementary_data.zip › TableS2_RAS_Variants_CompScores.xlsx › Sheet_1

Tumour cell responses to new fibroblast growth factor receptor tyrosine kinase inhibitors and identification of a gatekeeper mutation in FGFR3 as a mechanism of acquired resistance.

Chell V et al.

Oncogene, 2013

Mutation analysis in Costello syndrome: functional and structural characterization of the HRAS p.Lys117Arg mutation.

Denayer E et al.

Human Mutation, 2008

An unusual H-Ras mutant isolated from a human multiple myeloma line leads to transformation and factor-independent cell growth.

Crowder C et al.

Oncogene, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."