Varaico: Literature-Extracted Genetic Variants

Gene:HRAS
Variant:p.Q61E
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HRAS

NM_005343.4:p.Q61E

Associated Papers

Functional Analysis of Rare RAS Variants of Unknown Significance.

Park S et al.

Cancer Research Communications, 2025

40970755 (PubMed )
Supplement: crc-25-0188_supplementary_table_s4_suppst4.xlsx › Supplementary_Table_S4

Clinical features associated with NeoRAS wild-type metastatic colorectal cancer A SCRUM-Japan GOZILA substudy.

Osumi H et al.

Nature Communications, 2024

Case Report: Longitudinal monitoring of clonal evolution by circulating tumor DNA for resistance to anti-EGFR antibody in a case of metastatic colorectal cancer.

Sagawa T et al.

Frontiers in Oncology, 2023

Beyond structural bioinformatics for genomics with dynamics characterization of an expanded KRAS mutational landscape.

Ratnasinghe BD et al.

Computational and Structural Biotechnology Journal, 2023

Molecular and clinical profile of patients referred as Noonan or Noonan-like syndrome in Greece: a cohort of 86 patients.

Papadopoulos G et al.

European Journal of Pediatrics, 2022

Silent mutations reveal therapeutic vulnerability in RAS Q61 cancers.

Kobayashi Y et al.

Nature, 2022

The path to the clinic: a comprehensive review on direct KRASG12C inhibitors.

Kwan AK et al.

Journal of Experimental & Clinical Cancer Research : Cr, 2022

Detection of circulating tumor DNA in patients of operative colorectal and gastric cancers.

Suzuki T et al.

Oncotarget, 2020

32922660 (PubMed )
Supplement: oncotarget-11-3198-s002.xlsx › Table_1

Next-Generation Sequencing at High Sequencing Depth as a Tool to Study the Evolution of Metastasis Driven by Genetic Change Events of Lung Squamous Cell Carcinoma.

Mansour H et al.

Frontiers in Oncology, 2020

Targeted deep sequencing from multiple sources demonstrates increased NOTCH1 alterations in lung cancer patient plasma.

Liao Y et al.

Cancer Medicine, 2019

31369215 (PubMed )
Supplement: CAM4-8-5673-s008.xlsx › Supplementary_Table_S5

Understanding the impacts of missense mutations on structures and functions of human cancer-related genes: A preliminary computational analysis of the COSMIC Cancer Gene Census.

Malhotra S et al.

Plos One, 2019

A Comparative Analysis of Individual RAS Mutations in Cancer Biology.

Muñoz-Maldonado C et al.

Frontiers in Oncology, 2019

Molecular masquerading of rare EGFR L858M/L861R mutations as common L858R/L861Q mutations by PNA clamping assay.

Hong JH et al.

Pathology, 2017

RAS isoforms and mutations in cancer at a glance.

Hobbs GA et al.

Journal of Cell Science, 2016

Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

MacConaill LE et al.

The Journal of Molecular Diagnostics : Jmd, 2014

Structure-energy-based predictions and network modelling of RASopathy and cancer missense mutations.

Kiel C et al.

Molecular Systems Biology, 2014

24803665 (PubMed )
Supplement: MSB-10-5-727-s13.xls › energies

Common oncogenic mutations are infrequent in oral squamous cell carcinoma of Asian origin.

Zanaruddin SN et al.

Plos One, 2013

24224046 (PubMed )
Supplement: pone.0080229.s001.zip › File_S1 › Table_S4-PCR_and_Seq_Primers.xlsx › Sheet1

Electrostatic effects of mutations of Ras glutamine 61 measured using vibrational spectroscopy of a thiocyanate probe.

Stafford AJ et al.

Biochemistry, 2012

FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy.

Kompier LC et al.

Plos One, 2010

Role of glutamine-61 in the hydrolysis of GTP by p21H-ras: an experimental and theoretical study.

Frech M et al.

Biochemistry, 1994

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."