Associated Papers
The HRAS Variant c.175G>A (p.Ala59Thr) Causes a Predominantly Ectodermal Phenotype Lacking Classic Costello Syndrome Features.
Rautiainen N et al.
American Journal of Medical Genetics. Part A, 2026
Functional Analysis of Rare RAS Variants of Unknown Significance.
Park S et al.
Cancer Research Communications, 2025
40970755 (PubMed )
Supplement: crc-25-0188_supplementary_table_s5_suppst5.xlsx › Supplementary_Table_S5
Investigating the effects of cysteine-118 oxidation on G12D KRas structure and dynamics: insights from MD simulations.
Salamh S et al.
Journal of Biomolecular Structure & Dynamics, 2024
Clinical features associated with NeoRAS wild-type metastatic colorectal cancer A SCRUM-Japan GOZILA substudy.
Osumi H et al.
Nature Communications, 2024
Clinical-Molecular characteristics and Post-Translational modifications of colorectal cancer in north China: Implications for future targeted therapies.
Chi Y et al.
Gene, 2024
A very mild phenotype in six individuals of a three-generation family with the novel HRAS variant c.176C > G p.(Ala59Gly): Emergence of a new HRAS-related RASopathy distinct from Costello syndrome.
Frey T et al.
American Journal of Medical Genetics. Part A, 2023
Case Report: Longitudinal monitoring of clonal evolution by circulating tumor DNA for resistance to anti-EGFR antibody in a case of metastatic colorectal cancer.
Sagawa T et al.
Frontiers in Oncology, 2023
Delineating the RAS Conformational Landscape.
Parker MI et al.
Cancer Research, 2022
35536216 (PubMed )
Supplement: can-22-0804_supplementary_datasets_s1-s4_suppsds1-sds4.xlsx › Supplementary_Dataset_S1
Selective and noncovalent targeting of RAS mutants for inhibition and degradation.
Teng KW et al.
Nature Communications, 2021
33976200 (PubMed )
Supplement: 41467_2021_22969_MOESM1_ESM.pdf
Structures of N-terminally processed KRAS provide insight into the role of N-acetylation.
Dharmaiah S et al.
Scientific Reports, 2019
Comprehensive genomic profiling of 295 cases of clinically advanced urothelial carcinoma of the urinary bladder reveals a high frequency of clinically relevant genomic alterations.
Ross JS et al.
Cancer, 2016
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