Varaico: Literature-Extracted Genetic Variants

Gene:HRAS
Variant:p.Y40C
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HRAS

NM_005343.4:p.Y40C

Associated Papers

Integrated Analysis of Genomic and Immunological Features in Lung Adenocarcinoma With Micropapillary Component.

Zhang S et al.

Frontiers in Oncology, 2021

34221970 (PubMed )
Supplement: Table_5.xlsx › Supplementary_Table_S5

RAS and RHO family GTPase mutations in cancer: twin sons of different mothers?

Hodge RG et al.

Critical Reviews in Biochemistry and Molecular Biology, 2020

The RAS-Effector Interface: Isoform-Specific Differences in the Effector Binding Regions.

Nakhaeizadeh H et al.

Plos One, 2016

Duplication of Glu37 in the switch I region of HRAS impairs effector/GAP binding and underlies Costello syndrome by promoting enhanced growth factor-dependent MAPK and AKT activation.

Gremer L et al.

Human Molecular Genetics, 2010

A cross-talk between oncogenic Ras and tumor suppressor PTEN through FAK Tyr861 phosphorylation in NIH/3T3 mouse embryonic fibroblasts.

Bahk YY et al.

Biochemical and Biophysical Research Communications, 2008

Amino acids interfere with the ERK1/2-dependent control of macroautophagy by controlling the activation of Raf-1 in human colon cancer HT-29 cells.

Pattingre S et al.

The Journal of Biological Chemistry, 2003

Dissecting the roles of Raf- and PI3K-signalling pathways in melanoma formation and progression in a zebrafish model.

Michailidou C et al.

Disease Models & Mechanisms, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."