Associated Papers
Structural Insights into the SPRED1-Neurofibromin-KRAS Complex and Disruption of SPRED1-Neurofibromin Interaction by Oncogenic EGFR.
Yan W et al.
Cell Reports, 2020
Duplication of Glu37 in the switch I region of HRAS impairs effector/GAP binding and underlies Costello syndrome by promoting enhanced growth factor-dependent MAPK and AKT activation.
Gremer L et al.
Human Molecular Genetics, 2010
Fluoride complexes of oncogenic Ras mutants to study the Ras-RasGap interaction.
Gremer L et al.
Biological Chemistry, 2008
Selective inhibition of Ras interaction with its particular effector by synthetic peptides corresponding to the Ras effector region.
Ohnishi M et al.
The Journal of Biological Chemistry, 1998
Differential structural requirements for interaction of Ras protein with its distinct downstream effectors.
Akasaka K et al.
The Journal of Biological Chemistry, 1996
Three-dimensional structure of p21 in the active conformation and analysis of an oncogenic mutant.
Wittinghofer F et al.
Environmental Health Perspectives, 1991
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