Associated Papers
The small GTPase MRAS is a broken switch.
Bernal Astrain G et al.
Nature Communications, 2025
39809765 (PubMed )
Supplement: 41467_2025_55967_MOESM6_ESM.pdf
Tumor-derived RHOA mutants interact with effectors in the GDP-bound state.
Lin Y et al.
Nature Communications, 2024
Beyond structural bioinformatics for genomics with dynamics characterization of an expanded KRAS mutational landscape.
Ratnasinghe BD et al.
Computational and Structural Biotechnology Journal, 2023
Understanding the influence of AMG 510 on the structure of KRASG12C empowered by molecular dynamics simulation.
Li Y et al.
Computational and Structural Biotechnology Journal, 2022
NMR in integrated biophysical drug discovery for RAS: past, present, and future.
Marshall CB et al.
Journal of Biomolecular Nmr, 2020
Structures of N-terminally processed KRAS provide insight into the role of N-acetylation.
Dharmaiah S et al.
Scientific Reports, 2019
The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.
Kovalski JR et al.
Molecular Cell, 2019
KRAS Switch Mutants D33E and A59G Crystallize in the State 1 Conformation.
Lu J et al.
Biochemistry, 2018
Slow conformational dynamics of the guanine nucleotide-binding protein Ras complexed with the GTP analogue GTPgammaS.
Spoerner M et al.
The Febs Journal, 2007
Conformational states of Ras complexed with the GTP analogue GppNHp or GppCH2p: implications for the interaction with effector proteins.
Spoerner M et al.
Biochemistry, 2005
Ras interaction with two distinct binding domains in Raf-1 may be required for Ras transformation.
Drugan JK et al.
The Journal of Biological Chemistry, 1996
Select a paper to view details