Varaico: Literature-Extracted Genetic Variants

Gene:HRAS
Variant:p.F28L
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HRAS

NM_005343.4:p.F28L

Associated Papers

Beyond structural bioinformatics for genomics with dynamics characterization of an expanded KRAS mutational landscape.

Ratnasinghe BD et al.

Computational and Structural Biotechnology Journal, 2023

Development of a versatile HPLC-based method to evaluate the activation status of small GTPases.

Araki M et al.

The Journal of Biological Chemistry, 2021

RAS and RHO family GTPase mutations in cancer: twin sons of different mothers?

Hodge RG et al.

Critical Reviews in Biochemistry and Molecular Biology, 2020

Tumorigenesis: Mutant relationships.

Seton-Rogers S

Nature Reviews. Cancer, 2015

Diverging gain-of-function mechanisms of two novel KRAS mutations associated with Noonan and cardio-facio-cutaneous syndromes.

Cirstea IC et al.

Human Molecular Genetics, 2013

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.

Krauthammer M et al.

Nature Genetics, 2012

22842228 (PubMed )
Supplement: NIHMS390374-supplement-1.pdf

Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders.

Gremer L et al.

Human Mutation, 2011

Backbone dynamics of an oncogenic mutant of Cdc42Hs shows increased flexibility at the nucleotide-binding site.

Adams PD et al.

Biochemistry, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."