Varaico: Literature-Extracted Genetic Variants

Gene:HRH3
Variant:p.A280V
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HRH3

NM_007232.3:p.A280V

Associated Papers

Ligand-directed biased agonism at human histamine H3 receptor isoforms across Gαi/o- and β-arrestin2-mediated pathways.

Rahman SN et al.

Biochemical Pharmacology, 2024

Analysis of Missense Variants in the Human Histamine Receptor Family Reveals Increased Constitutive Activity of E4106.30×30K Variant in the Histamine H1 Receptor.

Ma X et al.

International Journal of Molecular Sciences, 2021

Alternative splicing event modifying ADGRL1/latrophilin-1 cytoplasmic tail promotes both opposing and dual cAMP signaling pathways.

Ovando-Zambrano JC et al.

Annals of the New York Academy of Sciences, 2019

The naturally occurring mutation Y197C does not affect the expression or signaling of the human histamine H3 receptor.

Flores-Clemente C et al.

Neuroscience Letters, 2017

Migraine Susceptibility Genes in Han Chinese of Fujian Province.

Lin QF et al.

Journal of Clinical Neurology (seoul, Korea), 2017

Polymorphisms and genetic linkage of histamine receptors.

Micallef S et al.

Life Sciences, 2013

A single-point mutation (Ala280Val) in the third intracellular loop alters the signalling properties of the human histamine H₃ receptor stably expressed in CHO-K1 cells.

Flores-Clemente C et al.

British Journal of Pharmacology, 2013

A280V polymorphism in the histamine H3 receptor as a risk factor for migraine.

Millán-Guerrero RO et al.

Archives of Medical Research, 2011

Structure of the human histamine H3 receptor gene (HRH3) and identification of naturally occurring variations.

Wiedemann P et al.

Journal of Neural Transmission (vienna, Austria : 1996), 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."