Varaico: Literature-Extracted Genetic Variants

Gene:HSP90AA1
Variant:p.E18V
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HSP90AA1

NM_005348.4:p.E18V

Associated Papers

Intramolecular interaction kinetically regulates fibril formation by human and mouse α-synuclein.

Ohgita T et al.

Scientific Reports, 2023

Mechanisms of enhanced aggregation and fibril formation of Parkinson's disease-related variants of α-synuclein.

Ohgita T et al.

Scientific Reports, 2022

A sensitive assay reveals structural requirements for α-synuclein fibril growth.

Dhavale DD et al.

The Journal of Biological Chemistry, 2017

A Novel Hsp90 Inhibitor Activates Compensatory Heat Shock Protein Responses and Autophagy and Alleviates Mutant A53T α-Synuclein Toxicity.

Xiong R et al.

Molecular Pharmacology, 2015

On the road to leucine-rich repeat kinase 2 signalling: evidence from cellular and in vivo studies.

Daniëls V et al.

Neuro-signals, 2011

Novel suppressors of alpha-synuclein toxicity identified using yeast.

Liang J et al.

Human Molecular Genetics, 2008

Part II: alpha-synuclein and its molecular pathophysiological role in neurodegenerative disease.

Dev KK et al.

Neuropharmacology, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."