Varaico: Literature-Extracted Genetic Variants

Gene:HSPA1A
Variant:p.K423E
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HSPA1A

NM_005345.6:p.K423E

Associated Papers

Candidate polymorphisms and susceptibility to inflammatory bowel disease: A systematic review and meta-analysis.

Tang L et al.

Gene, 2020

HSPA1A gene polymorphism rs1008438 is associated with susceptibility to acute mountain sickness in Han Chinese individuals.

Liu Z et al.

Molecular Genetics & Genomic Medicine, 2020

Interaction of heat shock protein 70 (HSP70) polymorphisms and occupational hazards increases the risk of hypertension in coke oven workers.

Zheng JP et al.

Occupational and Environmental Medicine, 2018

Association of A1538G and C2437T single nucleotide polymorphisms in heat shock protein-70 genes with diabetic nephropathy among South Indian population.

Dhamodharan U et al.

Bioscience Reports, 2017

The promoter polymorphisms of receptor for advanced glycation end products were associated with the susceptibility and progression of sepsis.

Shao Y et al.

Clinical Genetics, 2017

[Association between platelet-activating factor acetylhydrolase gene polymorphisms and gastrointestinal bleeding in children with Henoch-Schönlein purpura].

Wang BX et al.

Zhongguo Dang Dai Er Ke Za Zhi = Chinese Journal of Contemporary Pediatrics, 2017

Association of heat shock protein70-2 (HSP70-2) gene polymorphism with obesity.

Mardan-Nik M et al.

Annals of Human Biology, 2016

Heat shock protein 70-2 and tumor necrosis factor-α gene polymorphisms in Chinese children with Henoch-Schönlein purpura.

Ding GX et al.

World Journal of Pediatrics : Wjp, 2016

A conserved linkage group on chromosome 6, the 8.1 ancestral haplotype, is a predisposing factor of chronic rhinosinusitis associated with nasal polyposis in aspirin-sensitive Hungarians.

Szabó K et al.

Human Immunology, 2015

An ADAM10 promoter polymorphism is a functional variant in severe sepsis patients and confers susceptibility to the development of sepsis.

Cui L et al.

Critical Care (london, England), 2015

Association of heat shock protein70-2 (HSP70-2) gene polymorphism with coronary artery disease in an Iranian population.

Mardan-Nik M et al.

Gene, 2014

Are Hsp70 protein expression and genetic polymorphism implicated in multiple sclerosis inflammation?

Boiocchi C et al.

Journal of Neuroimmunology, 2014

Heat shock protein 70 gene polymorphisms are associated with paranoid schizophrenia in the Polish population.

Kowalczyk M et al.

Cell Stress & Chaperones, 2014

Association among 1267 A/G HSP70-2, -308 G/A TNF-α polymorphisms and pro-inflammatory plasma mediators in old ZincAge population.

Giacconi R et al.

Biogerontology, 2014

Single-nucleotide polymorphisms in Toll-like receptor (TLR)-2, TLR4 and heat shock protein 70 genes and susceptibility to scrub typhus.

Janardhanan J et al.

Journal of Human Genetics, 2013

[Association of tumor necrosis factor-alpha gene polymorphisms with Henoch-Schonlein purpura nephritis in children].

Wang JJ et al.

Zhongguo Dang Dai Er Ke Za Zhi = Chinese Journal of Contemporary Pediatrics, 2013

Analysis of the 8.1 ancestral MHC haplotype in severe, pneumonia-related sepsis.

Aladzsity I et al.

Clinical Immunology (orlando, Fla.), 2011

Frequent occurrence of conserved extended haplotypes (CEHs) in two Caucasian populations.

Szilágyi A et al.

Molecular Immunology, 2010

Interactive association of heat shock protein 70 genes variants with natural longevity in Xinjiang Hetian Uygur ethnicity.

Li J et al.

Translational Research : the Journal of Laboratory and Clinical Medicine, 2009

Linkage analysis of the C4A/C4B copy number variation and polymorphisms of the adjacent steroid 21-hydroxylase gene in a healthy population.

Blaskó B et al.

Molecular Immunology, 2009

Interacting contribution of the five polymorphisms in three genes of Hsp70 family to essential hypertension in Uygur ethnicity.

Li JX et al.

Cell Stress & Chaperones, 2009

Genetic interaction of Hsp70 family genes polymorphisms with high-altitude pulmonary edema among Chinese railway constructors at altitudes exceeding 4000 meters.

Qi Y et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2009

HLA-association of serum levels of natural antibodies.

Pozsonyi E et al.

Molecular Immunology, 2009

Pro-inflammatory genetic background and zinc status in old atherosclerotic subjects.

Giacconi R et al.

Ageing Research Reviews, 2008

Polymorphisms of TNF-alpha and LT-alpha genes in multiple myeloma.

Kádár K et al.

Leukemia Research, 2008

Autoimmune-associated HLA-B8-DR3 haplotypes in Asian Indians are unique in C4 complement gene copy numbers and HSP-2 1267A/G.

Kaur G et al.

Human Immunology, 2008

Polymorphisms of the MCP-1 and HSP70-2 genes in Korean patients with alcoholic chronic pancreatitis.

Lee SH et al.

Digestive Diseases and Sciences, 2008

The 8.1 ancestral MHC haplotype is strongly associated with colorectal cancer risk.

Tóth EK et al.

International Journal of Cancer, 2007

Effects of polymorphisms of heat shock protein 70 gene on ischemic stroke, and interaction with smoking in China.

Liu J et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2007

The HLA 8.1 ancestral haplotype is strongly linked to the C allele of -429T>C promoter polymorphism of receptor of the advanced glycation endproduct (RAGE) gene. Haplotype-independent association of the -429C allele with high hemoglobinA1C levels in diabetic patients.

Laki J et al.

Molecular Immunology, 2007

Frequency of carriers of 8.1 ancestral haplotype and its fragments in two Caucasian populations.

Kiszel P et al.

Immunological Investigations, 2007

The 8.1 ancestral MHC haplotype is associated with delayed onset of colonization in cystic fibrosis.

Laki J et al.

International Immunology, 2006

1267 HSP70-2 polymorphism as a risk factor for carotid plaque rupture and cerebral ischaemia in old type 2 diabetes-atherosclerotic patients.

Giacconi R et al.

Mechanisms of Ageing and Development, 2005

Polymorphism of the TNF-alpha, HSP70-2, and CD14 genes increases susceptibility to severe acute pancreatitis.

Balog A et al.

Pancreas, 2005

[Polymorphism of angiotensin converting enzyme gene and natural longevity in the Xinjiang Uygur people: an association study].

Wufuer M et al.

Zhonghua Yi Xue Za Zhi, 2004

Ethnic differences of polymorphisms in cytokine and innate immune system genes in pregnant women.

Nguyen DP et al.

Obstetrics and Gynecology, 2004

The contribution of HLA genes to IBD susceptibility and phenotype.

Yap LM et al.

Best Practice & Research. Clinical Gastroenterology, 2004

Analysis of heat-shock protein 70 gene polymorphisms and the risk of Parkinson's disease.

Wu YR et al.

Human Genetics, 2004

Histocompatibility leucocyte antigens and closely linked immunomodulatory genes in autoimmune thyroid disease.

Hunt PJ et al.

Clinical Endocrinology, 2001

Heat shock protein 70 gene polymorphism in Japanese patients with multiple sclerosis.

Niino M et al.

Tissue Antigens, 2001

HSP70 gene polymorphisms in ankylosing spondylitis.

Fraile A et al.

Tissue Antigens, 1998

Effect of ZIP2 Gln/Arg/Leu (rs2234632) polymorphism on zinc homeostasis and inflammatory response following zinc supplementation.

Giacconi R et al.

Biofactors (oxford, England), 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."