Associated Papers
SLITRK2 variants associated with neurodevelopmental disorders impair excitatory synaptic function and cognition in mice.
El Chehadeh S et al.
Nature Communications, 2022
35840571 (PubMed )
Supplement: 41467_2022_31566_MOESM1_ESM.pdf
Structures of a deAMPylation complex rationalise the switch between antagonistic catalytic activities of FICD.
Perera LA et al.
Nature Communications, 2021
Factor VIII exhibits chaperone-dependent and glucose-regulated reversible amyloid formation in the endoplasmic reticulum.
Poothong J et al.
Blood, 2020
An oligomeric state-dependent switch in the ER enzyme FICD regulates AMPylation and deAMPylation of BiP.
Perera LA et al.
The Embo Journal, 2019
MANF antagonizes nucleotide exchange by the endoplasmic reticulum chaperone BiP.
Yan Y et al.
Nature Communications, 2019
A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response.
Amin-Wetzel N et al.
Cell, 2017
AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation.
Preissler S et al.
Elife, 2017
FICD acts bifunctionally to AMPylate and de-AMPylate the endoplasmic reticulum chaperone BiP.
Preissler S et al.
Nature Structural & Molecular Biology, 2017
AMPylation matches BiP activity to client protein load in the endoplasmic reticulum.
Preissler S et al.
Elife, 2015
Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3.
Petrova K et al.
The Embo Journal, 2008
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