Varaico: Literature-Extracted Genetic Variants

Gene:HSPA5
Variant:p.G226D
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HSPA5

NM_005347.5:p.G226D

Associated Papers

AMPylation matches BiP activity to client protein load in the endoplasmic reticulum.

Preissler S et al.

Elife, 2015

Mutation of the ATP-binding pocket of SSA1 indicates that a functional interaction between Ssa1p and Ydj1p is required for post-translational translocation into the yeast endoplasmic reticulum.

McClellan AJ et al.

Genetics, 2000

In vitro dissociation of BiP-peptide complexes requires a conformational change in BiP after ATP binding but does not require ATP hydrolysis.

Wei J et al.

The Journal of Biological Chemistry, 1995

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."