Varaico: Literature-Extracted Genetic Variants

Gene:HSPA8
Variant:p.T204A
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HSPA8

NM_006597.6:p.T204A

Associated Papers

The ALS-associated E425K mutation uncouples DNAJC7 from the Hsp70 chaperone cycle.

Elmaleh B et al.

The Febs Journal, 2026

S-Glutathionylation of human inducible Hsp70 reveals a regulatory mechanism involving the C-terminal α-helical lid.

Yang J et al.

The Journal of Biological Chemistry, 2020

PES inhibits human-inducible Hsp70 by covalent targeting of cysteine residues in the substrate-binding domain.

Yang J et al.

The Journal of Biological Chemistry, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."