Varaico: Literature-Extracted Genetic Variants

Gene:HTR2A
Variant:p.A447V
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HTR2A

NM_000621.5:p.A447V

Associated Papers

5-HT2A SNPs Alter the Pharmacological Signaling of Potentially Therapeutic Psychedelics.

Schmitz GP et al.

Acs Chemical Neuroscience, 2022

Targeted next-generation sequencing provides novel clues for associated epilepsy and cardiac conduction disorder/SUDEP.

Coll M et al.

Plos One, 2017

Functional SNPs in genes encoding the 5-HT2A receptor modify the affinity and potency of several atypical antipsychotic drugs.

Davies MA et al.

Biological Research for Nursing, 2011

Polymorphisms of the 5-HT2A receptor gene and clinical response to olanzapine in paranoid schizophrenia.

Olajossy-Hilkesberger L et al.

Neuropsychobiology, 2011

An improved in silico selection of phenotype affecting polymorphisms in SLC6A4, HTR1A and HTR2A genes.

Piva F et al.

Human Psychopharmacology, 2010

Association analysis between the C516T polymorphism in the 5-HT2A receptor gene and schizophrenia.

Bertola V et al.

Arquivos De Neuro-psiquiatria, 2007

[Alcohol dependence and polymorphisms of serotonin-related genes].

Gorwood P et al.

Medecine Sciences : M/s, 2004

Human genetic variations in the 5HT2A receptor: a single nucleotide polymorphism identified with altered response to clozapine.

Harvey L et al.

Pharmacogenetics, 2003

Family-based association study of the serotonin-2A receptor gene (5-HT2A) and bipolar disorder.

Ni X et al.

Neuromolecular Medicine, 2002

A naturally occurring amino acid substitution of the human serotonin 5-HT2A receptor influences amplitude and timing of intracellular calcium mobilization.

Ozaki N et al.

Journal of Neurochemistry, 1997

Pharmacologic analysis of non-synonymous coding h5-HT2A SNPs reveals alterations in atypical antipsychotic and agonist efficacies.

Davies MA et al.

The Pharmacogenomics Journal, 0

Impact of the -1438G>a polymorphism in the serotonin 2A receptor gene on anthropometric profile and obesity risk: a case-control study in a Spanish Mediterranean population.

Sorlí JV et al.

Appetite, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."