Varaico: Literature-Extracted Genetic Variants

Gene:HTR2A
Variant:p.S34S
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HTR2A

NM_000621.5:p.S34S

Associated Papers

Analgesic therapy failure in a COMT HPS/HPS diplotype carrier heterozygous for the CYP2D6 *4 allele with fibromyalgia-a case report.

Bollinger A et al.

Pain Reports, 2025

39995492 (PubMed )
Supplement: painreports-10-e1248-s001.pdf

The pharmacogenomic landscape in the Chinese: An analytics of pharmacogenetic variants in 206,640 individuals.

Wang LY et al.

Innovation (cambridge (mass.)), 2025

39991480 (PubMed )
Supplement: mmc6.xlsx › Sheet1

The impact of genetic variability on Alzheimer's therapies: obstacles for pharmacogenetic progress.

Cacabelos R et al.

Expert Opinion on Drug Metabolism & Toxicology, 2025

The polymorphisms of candidate pharmacokinetic and pharmacodynamic genes and their pharmacogenetic impacts on the effectiveness of risperidone maintenance therapy among Saudi children with autism.

Shilbayeh SAR et al.

European Journal of Clinical Pharmacology, 2024

Pharmacogenetics of anxiety and depression in Alzheimer's disease.

Cacabelos R et al.

Pharmacogenomics, 2023

Genetic Contribution of the Adrenergic, Cholinergic, and Serotonergic Systems to Leiomyoma Development and Treatment.

Inácio  et al.

International Journal of Molecular and Cellular Medicine, 2023

Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study.

Fjukstad KK et al.

The Pharmacogenomics Journal, 2021

The serotonin receptor 2A (HTR2A) rs6313 variant is associated with higher ongoing pain and signs of central sensitization in neuropathic pain patients.

Sachau J et al.

European Journal of Pain (london, England), 2021

Development and Analytical Validation of a 29 Gene Clinical Pharmacogenetic Genotyping Panel: Multi-Ethnic Allele and Copy Number Variant Detection.

Scott SA et al.

Clinical and Translational Science, 2021

Common HTR2A variants and 5-HTTLPR are not associated with human in vivo serotonin 2A receptor levels.

Spies M et al.

Human Brain Mapping, 2020

Association of the Serotonin 2A Receptor rs6311 Polymorphism with Diurnal Preference in Koreans.

Yeom JW et al.

Psychiatry Investigation, 2020

A novel patient-derived organoids-based xenografts model for preclinical drug response testing in patients with colorectal liver metastases.

Jian M et al.

Journal of Translational Medicine, 2020

32532289 (PubMed )
Supplement: 12967_2020_2407_MOESM2_ESM.xlsx › Table_S1A_356_SNV

Genetic association analysis of 5-HTR2A gene variants in eating disorders in a Mexican population.

Genis-Mendoza AD et al.

Brain and Behavior, 2019

Dopamine (DRD2) and Serotonin (HTR2A, 2C) Receptor Gene Polymorphisms do not influence early response to Risperidone in South Indian Patients with Schizophrenia.

Alladi CG et al.

Fundamental & Clinical Pharmacology, 2019

Association between serotonin 2A receptor genetic variations, stressful life events and suicide.

Ghasemi A et al.

Gene, 2018

Association of serotonin receptor 2a haplotypes with obsessive-compulsive disorder and its treatment response in Iranian patients: a genetic and pharmacogenetic study.

Sina M et al.

Neuropsychiatric Disease and Treatment, 2018

Novel human genome variants associated with alcohol use disorders identified in a Lithuanian cohort.

Baronas K et al.

Acta Medica Lituanic, 2018

A review of the role of serotonin system genes in obsessive-compulsive disorder.

Sinopoli VM et al.

Neuroscience and Biobehavioral Reviews, 2017

Serotonin-Related Gene Variants in Patients with Irritable Bowel Syndrome and Depressive or Anxiety Disorders.

Grzesiak M et al.

Gastroenterology Research and Practice, 2017

Pharmacogenetic tests for antipsychotic medications: clinical implications and considerations.

Eum S et al.

Dialogues in Clinical Neuroscience, 2016

A review of genetic alterations in the serotonin pathway and their correlation with psychotic diseases and response to atypical antipsychotics.

Baou M et al.

Schizophrenia Research, 2016

Obstructive sleep apnea syndrome susceptible genes in the Chinese population: a meta-analysis of 21 case-control studies.

Lan F et al.

Sleep & Breathing = Schlaf & Atmung, 2015

PharmGKB summary: Efavirenz pathway, pharmacokinetics.

McDonagh EM et al.

Pharmacogenetics and Genomics, 2015

Identifying genetic loci associated with antidepressant drug response with drug-gene interaction models in a population-based study.

Noordam R et al.

Journal of Psychiatric Research, 2015

Obstructive Sleep Apnea Susceptibility Genes in Chinese Population: A Field Synopsis and Meta-Analysis of Genetic Association Studies.

Sun J et al.

Plos One, 2015

Converging translational evidence for the involvement of the serotonin 2A receptor gene in major depressive disorder.

Petit AC et al.

Progress in Neuro-psychopharmacology & Biological Psychiatry, 2014

Influence of 5-HTR2A genetic polymorphisms on the efficacy of antidepressants in the treatment of major depressive disorder: a meta-analysis.

Lin JY et al.

Journal of Affective Disorders, 2014

A systematic review and meta-analysis of the association between serotonergic gene polymorphisms and obstructive sleep apnea syndrome.

Xu H et al.

Plos One, 2014

Association between 5-HT2A receptor polymorphisms and risk of obstructive sleep apnea and hypopnea syndrome: a systematic review and meta-analysis.

Zhao Y et al.

Gene, 2013

Family-based study of HTR2A in suicide attempts: observed gene, gene × environment and parent-of-origin associations.

Ben-Efraim YJ et al.

Molecular Psychiatry, 2013

Association of common genetic variants with risperidone adverse events in a Spanish schizophrenic population.

Almoguera B et al.

The Pharmacogenomics Journal, 2013

Multiple regulatory variants modulate expression of 5-hydroxytryptamine 2A receptors in human cortex.

Smith RM et al.

Biological Psychiatry, 2013

Association and CpG SNP analysis of HTR4 polymorphisms with suicidal behavior in subjects with schizophrenia.

Polsinelli G et al.

Journal of Neural Transmission (vienna, Austria : 1996), 2013

The association of attempted suicide with genetic variants in the SLC6A4 and TPH genes depends on the definition of suicidal behavior: a systematic review and meta-analysis.

Clayden RC et al.

Translational Psychiatry, 2012

23032942 (PubMed )
Supplement: tp201296x1.doc

Association of genetic, psychological and behavioral factors with sleep bruxism in a Japanese population.

Abe Y et al.

Journal of Sleep Research, 2012

Irritable bowel syndrome: methods, mechanisms, and pathophysiology. Genetic epidemiology and pharmacogenetics in irritable bowel syndrome.

Camilleri M et al.

American Journal of Physiology. Gastrointestinal and Liver Physiology, 2012

Association of the 5-HT2A receptor gene polymorphisms with obstructive sleep apnea hypopnea syndrome in Chinese Han population.

Yin G et al.

Acta Oto-laryngologica, 2012

The CC genotype in HTR2A T102C polymorphism is associated with behavioral impulsivity in alcohol-dependent patients.

Jakubczyk A et al.

Journal of Psychiatric Research, 2012

The c.1460C>T polymorphism of MAO-A is associated with the risk of depression in postmenopausal women.

Słopień R et al.

Thescientificworldjournal, 2012

[Distribution of serotonin transporter 5-HTTLPR gene polymorphism in population of the North-West of Russia].

Smirnova TIu et al.

Advances in Gerontology = Uspekhi Gerontologii, 2012

Functional genomics of serotonin receptor 2A (HTR2A): interaction of polymorphism, methylation, expression and disease association.

Falkenberg VR et al.

Neuromolecular Medicine, 2011

Pharmacogenetics of antidepressants.

Crisafulli C et al.

Frontiers in Pharmacology, 2011

[Distribution of structural polymorphisms of angiotensin-converting enzyme and serotonin receptor 5-HT2A genes among long-livers of North-Western Russia].

Smirnova TIu et al.

Advances in Gerontology = Uspekhi Gerontologii, 2011

Role of 2 common variants of 5HT2A gene in medication overuse headache.

Terrazzino S et al.

Headache, 2010

Antagonistic coevolution of two imprinted loci with pleiotropic effects.

Wilkins JF

Evolution; International Journal of Organic Evolution, 2010

Serotonergic system genes in psychosis of Alzheimer dementia: meta-analysis.

Ramanathan S et al.

The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry, 2009

The combined effects of the 5-HTTLPR and 5-HTR1A genes modulates the relationship between negative life events and major depressive disorder in a Chinese population.

Zhang K et al.

Journal of Affective Disorders, 2009

Association between Val66Met brain-derived neurotrophic factor (BDNF) gene polymorphism and post-treatment relapse in alcohol dependence.

Wojnar M et al.

Alcoholism, Clinical and Experimental Research, 2009

Polymorphisms in the SLC6A4 and HTR2A genes influence treatment outcome following antidepressant therapy.

Wilkie MJ et al.

The Pharmacogenomics Journal, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."