Varaico: Literature-Extracted Genetic Variants

Gene:HTR2A
Variant:p.T25N
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HTR2A

NM_000621.5:p.T25N

Associated Papers

Germline variants in UHRF1 are associated with multilocus imprinting disturbance in humans and mice.

Ochoa E et al.

Proceedings of the National Academy of Sciences of the United States of America, 2025

40825131 (PubMed )
Supplement: pnas.2505884122.sd01.xlsx › Sheet1

The landscape of rare genetic variants in familial Waldenström macroglobulinemia.

Pemov A et al.

Blood Neoplasia, 2024

39036705 (PubMed )
Supplement: BNEO_NEO-2023-000111-mmc8.xlsx › Supplementary_Table_7C

5-HT2A SNPs Alter the Pharmacological Signaling of Potentially Therapeutic Psychedelics.

Schmitz GP et al.

Acs Chemical Neuroscience, 2022

Precision Health Resource of Control iPSC Lines for Versatile Multilineage Differentiation.

Hildebrandt MR et al.

Stem Cell Reports, 2019

31813827 (PubMed )
Supplement: mmc2.xlsx › SNVs

A review of genetic alterations in the serotonin pathway and their correlation with psychotic diseases and response to atypical antipsychotics.

Baou M et al.

Schizophrenia Research, 2016

Association of the HTR2A gene with alcohol and heroin abuse.

Cao J et al.

Human Genetics, 2014

Large-scale polymorphism discovery in macaque G-protein coupled receptors.

Goswami DB et al.

Bmc Genomics, 2013

24119066 (PubMed )
Supplement: 1471-2164-14-703-S4.xlsx › Sheet1

Computational exploration of polymorphisms in 5-hydoxytryptamine 5-HT₁A and 5-HT₂A receptors associated with psychiatric disease.

Dass JF et al.

Gene, 2012

Meta-analysis of genetic association studies on bipolar disorder.

Seifuddin F et al.

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2012

Functional SNPs in genes encoding the 5-HT2A receptor modify the affinity and potency of several atypical antipsychotic drugs.

Davies MA et al.

Biological Research for Nursing, 2011

Polymorphisms of the 5-HT2A receptor gene and clinical response to olanzapine in paranoid schizophrenia.

Olajossy-Hilkesberger L et al.

Neuropsychobiology, 2011

An improved in silico selection of phenotype affecting polymorphisms in SLC6A4, HTR1A and HTR2A genes.

Piva F et al.

Human Psychopharmacology, 2010

Pharmacogenetics of selective serotonin reuptake inhibitors and associated adverse drug reactions.

Thomas KL et al.

Pharmacotherapy, 2009

HTR2A variation and sudden infant death syndrome: a case-control analysis.

Rand CM et al.

Acta Paediatrica (oslo, Norway : 1992), 2009

Antipsychotic-induced extrapyramidal symptoms in patients with schizophrenia: associations with dopamine and serotonin receptor and transporter polymorphisms.

Güzey C et al.

European Journal of Clinical Pharmacology, 2007

Association analysis between the C516T polymorphism in the 5-HT2A receptor gene and schizophrenia.

Bertola V et al.

Arquivos De Neuro-psiquiatria, 2007

Analysis of SNP profiles in patients with major depressive disorder.

Kõks S et al.

The International Journal of Neuropsychopharmacology, 2006

[Alcohol dependence and polymorphisms of serotonin-related genes].

Gorwood P et al.

Medecine Sciences : M/s, 2004

Lack of association between 5HT2A receptor gene haplotype, bipolar disorder and its clinical subtypes in a West European sample.

Etain B et al.

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2004

Association study of serotonin-2A receptor gene polymorphism and panic disorder in patients from Canada and Germany.

Rothe C et al.

Neuroscience Letters, 2004

Linkage and association between serotonin 2A receptor gene polymorphisms and bipolar I disorder.

Ranade SS et al.

American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics, 2003

Human genetic variations in the 5HT2A receptor: a single nucleotide polymorphism identified with altered response to clozapine.

Harvey L et al.

Pharmacogenetics, 2003

Genetic predisposition to neuroleptic malignant syndrome : implications for antipsychotic therapy.

Kawanishi C

American Journal of Pharmacogenomics : Genomics-related Research in Drug Development and Clinical Practice, 2003

Family-based association study of the serotonin-2A receptor gene (5-HT2A) and bipolar disorder.

Ni X et al.

Neuromolecular Medicine, 2002

Refined localization of a gene for pediatric gastroesophageal reflux makes HTR2A an unlikely candidate gene.

Hu FZ et al.

Human Genetics, 2000

Serotonin-2A receptor gene is not associated with symptomatology of schizophrenia.

Serretti A et al.

American Journal of Medical Genetics, 2000

Pharmacogenetics of schizophrenia.

Cichon S et al.

American Journal of Medical Genetics, 2000

Lack of association between neuroleptic malignant syndrome and polymorphisms in the 5-HT1A and 5-HT2A receptor genes.

Kawanishi C et al.

The American Journal of Psychiatry, 1998

A family based association study of T102C polymorphism in 5HT2A and schizophrenia plus identification of new polymorphisms in the promoter.

Spurlock G et al.

Molecular Psychiatry, 1998

Genetic variation of the 5-HT2A receptor gene and bipolar affective disorder.

Gutiérrez B et al.

Human Genetics, 1997

5-HT2A receptor and bipolar affective disorder: association studies in affected patients.

Arranz MJ et al.

Neuroscience Letters, 1997

Lack of allelic association between 102T/C polymorphism of serotonin receptor type 2A gene and schizophrenia in Chinese.

Chen CH et al.

Psychiatric Genetics, 1997

Association between schizophrenia and T102C polymorphism of the 5-hydroxytryptamine type 2a-receptor gene. European Multicentre Association Study of Schizophrenia (EMASS) Group.

Williams J et al.

Lancet (london, England), 1996

Systematic screening for mutations in the human serotonin-2A (5-HT2A) receptor gene: identification of two naturally occurring receptor variants and association analysis in schizophrenia.

Erdmann J et al.

Human Genetics, 1996

Pharmacologic analysis of non-synonymous coding h5-HT2A SNPs reveals alterations in atypical antipsychotic and agonist efficacies.

Davies MA et al.

The Pharmacogenomics Journal, 0

Impact of the -1438G>a polymorphism in the serotonin 2A receptor gene on anthropometric profile and obesity risk: a case-control study in a Spanish Mediterranean population.

Sorlí JV et al.

Appetite, 0

Negative association between T102C polymorphism of the 5-HT2a receptor gene and schizophrenia in Japan.

Shinkai T et al.

Human Heredity, 0

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