Varaico: Literature-Extracted Genetic Variants

Gene:HTR3A
Variant:p.L14L
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HTR3A

NM_000869.6:p.L14L

Associated Papers

The serotonin receptor 3E variant is a risk factor for female IBS-D.

Fritz N et al.

Journal of Molecular Medicine (berlin, Germany), 2022

Serotonin type 3 receptor subunit gene polymorphisms associated with psychosomatic symptoms in irritable bowel syndrome: A multicenter retrospective study.

Berens S et al.

World Journal of Gastroenterology, 2022

Ethnic differences in genetic polymorphism associated with irritable bowel syndrome.

Xiao QY et al.

World Journal of Gastroenterology, 2020

5'UTR polymorphism in the serotonergic receptor HTR3A gene is differently associated with striatal Dopamine D2/D3 receptor availability in the right putamen in Fibromyalgia patients and healthy controls-Preliminary evidence.

Ledermann K et al.

Synapse (new York, N.y.), 2020

Candidate single nucleotide polymorphisms of irritable bowel syndrome: a systemic review and meta-analysis.

Zhu S et al.

Bmc Gastroenterology, 2019

31615448 (PubMed )
Supplement: 12876_2019_1084_MOESM1_ESM.docx

Abnormalities of mucosal serotonin metabolism and 5-HT3 receptor subunit 3C polymorphism in irritable bowel syndrome with diarrhoea predict responsiveness to ondansetron.

Gunn D et al.

Alimentary Pharmacology & Therapeutics, 2019

HTR3A and HTR3E gene polymorphisms and diarrhea predominant irritable bowel syndrome risk: evidence from a meta-analysis.

Guan T et al.

Oncotarget, 2017

The Human Serotonin Type 3 Receptor Gene (HTR3A-E) Allelic Variant Database.

Celli J et al.

Human Mutation, 2017

Genetic polymorphism in pathogenesis of irritable bowel syndrome.

Cheung CK et al.

World Journal of Gastroenterology, 2014

5-HT3 receptor influences the washing phenotype and visual organization in obsessive-compulsive disorder supporting 5-HT3 receptor antagonists as novel treatment option.

Lennertz L et al.

European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology, 2014

[Association between diarrhea-predominant irritable bowel syndrome and HTR3A, HTR3E gene polymorphism in Yangzhou,Jiangsu province, China].

Zhang Y et al.

Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi, 2013

Genetics of human gastrointestinal sensation.

Camilleri M

Neurogastroenterology and Motility, 2013

Irritable bowel syndrome: methods, mechanisms, and pathophysiology. Genetic epidemiology and pharmacogenetics in irritable bowel syndrome.

Camilleri M et al.

American Journal of Physiology. Gastrointestinal and Liver Physiology, 2012

Replication of functional serotonin receptor type 3A and B variants in bipolar affective disorder: a European multicenter study.

Hammer C et al.

Translational Psychiatry, 2012

G-protein β3 subunit 825CC genotype is associated with postprandial distress syndrome with impaired gastric emptying and with the feeling of hunger in Japanese.

Shimpuku M et al.

Neurogastroenterology and Motility, 2011

Serotonin receptor 3A polymorphism c.-42C > T is associated with severe dyspepsia.

Mujakovic S et al.

Bmc Medical Genetics, 2011

The HTR3A polymorphism c. -42C>T is associated with amygdala responsiveness in patients with irritable bowel syndrome.

Kilpatrick LA et al.

Gastroenterology, 2011

Impact of the HTR3A gene with early life trauma on emotional brain networks and depressed mood.

Gatt JM et al.

Depression and Anxiety, 2010

Genetic approaches to functional gastrointestinal disorders.

Saito YA et al.

Gastroenterology, 2010

Functional variants of the serotonin receptor type 3A and B gene are associated with eating disorders.

Hammer C et al.

Pharmacogenetics and Genomics, 2009

The 5-HT3 receptor--the relationship between structure and function.

Barnes NM et al.

Neuropharmacology, 2009

First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndrome.

Kapeller J et al.

Human Molecular Genetics, 2008

Distinguishable haplotype blocks in the HTR3A and HTR3B region in the Japanese reveal evidence of association of HTR3B with female major depression.

Yamada K et al.

Biological Psychiatry, 2006

Serotonin receptor genes HTR3A and HTR3B are not involved in Gilles de la Tourette syndrome.

Niesler B et al.

Psychiatric Genetics, 2005

Mutational analysis of serotonin receptor genes: HTR3A and HTR3B in fibromyalgia patients.

Frank B et al.

Clinical Rheumatology, 2004

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."