Varaico: Literature-Extracted Genetic Variants

Gene:HTR3A
Variant:p.R432Q
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HTR3A

NM_000869.6:p.R432Q

Associated Papers

Rings of charge within the extracellular vestibule influence ion permeation of the 5-HT3A receptor.

Livesey MR et al.

The Journal of Biological Chemistry, 2011

Novel structural determinants of single channel conductance and ion selectivity in 5-hydroxytryptamine type 3 and nicotinic acetylcholine receptors.

Peters JA et al.

The Journal of Physiology, 2010

Single-channel study of the binding-gating coupling in the slowly desensitizing chimeric alpha7-5HT3A receptor.

Bernal JA et al.

Febs Letters, 2009

Structural determinants of Ca2+ permeability and conduction in the human 5-hydroxytryptamine type 3A receptor.

Livesey MR et al.

The Journal of Biological Chemistry, 2008

Modular design of Cys-loop ligand-gated ion channels: functional 5-HT3 and GABA rho1 receptors lacking the large cytoplasmic M3M4 loop.

Jansen M et al.

The Journal of General Physiology, 2008

Common determinants of single channel conductance within the large cytoplasmic loop of 5-hydroxytryptamine type 3 and alpha4beta2 nicotinic acetylcholine receptors.

Hales TG et al.

The Journal of Biological Chemistry, 2006

Ligand-gated ion channels: mechanisms underlying ion selectivity.

Keramidas A et al.

Progress in Biophysics and Molecular Biology, 2004

The 5-hydroxytryptamine type 3 (5-HT3) receptor reveals a novel determinant of single-channel conductance.

Peters JA et al.

Biochemical Society Transactions, 2004

A cytoplasmic region determines single-channel conductance in 5-HT3 receptors.

Kelley SP et al.

Nature, 2003

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