Varaico: Literature-Extracted Genetic Variants

Gene:HTRA2
Variant:p.S400A
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HTRA2

NM_013247.5:p.S400A

Associated Papers

Phosphorylation of HtrA2 by cyclin-dependent kinase-5 is important for mitochondrial function.

Fitzgerald JC et al.

Cell Death and Differentiation, 2012

Loss-of-function analysis suggests that Omi/HtrA2 is not an essential component of the PINK1/PARKIN pathway in vivo.

Yun J et al.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2008

The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1.

Plun-Favreau H et al.

Nature Cell Biology, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."