Varaico: Literature-Extracted Genetic Variants

Gene:HTRA2
Variant:p.R404W
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HTRA2

NM_013247.5:p.R404W

Associated Papers

The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals.

Cao Y et al.

Cell Research, 2020

32355288 (PubMed )
Supplement: 41422_2020_322_MOESM14_ESM.xlsx › S7

modPDZpep: a web resource for structure based analysis of human PDZ-mediated interaction networks.

Sain N et al.

Biology Direct, 2016

27655048 (PubMed )
Supplement: 13062_2016_151_MOESM1_ESM.xls › Sheet4

HTRA2 variations in Taiwanese Parkinson's disease.

Chen CM et al.

Journal of Neural Transmission (vienna, Austria : 1996), 2014

Phosphorylation of HtrA2 by cyclin-dependent kinase-5 is important for mitochondrial function.

Fitzgerald JC et al.

Cell Death and Differentiation, 2012

Novel variant Pro143Ala in HTRA2 contributes to Parkinson's disease by inducing hyperphosphorylation of HTRA2 protein in mitochondria.

Lin CH et al.

Human Genetics, 2011

Genetic variations of Omi/HTRA2 in Chinese patients with Parkinson's disease.

Wang CY et al.

Brain Research, 2011

Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin.

Tain LS et al.

Cell Death and Differentiation, 2009

Parkinson's disease: from monogenic forms to genetic susceptibility factors.

Lesage S et al.

Human Molecular Genetics, 2009

Genetic variation of Omi/HtrA2 and Parkinson's disease.

Ross OA et al.

Parkinsonism & Related Disorders, 2008

Genetic variability in the mitochondrial serine protease HTRA2 contributes to risk for Parkinson disease.

Bogaerts V et al.

Human Mutation, 2008

Genetic findings in Parkinson's disease and translation into treatment: a leading role for mitochondria?

Bogaerts V et al.

Genes, Brain, and Behavior, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."