Associated Papers
The N17 domain of huntingtin as a multifaceted player in Huntington's disease.
Cho H
Frontiers in Molecular Biosciences, 2024
IKBKB reduces huntingtin aggregation by phosphorylating serine 13 via a non-canonical IKK pathway.
Cariulo C et al.
Life Science Alliance, 2023
TBK1 phosphorylates mutant Huntingtin and suppresses its aggregation and toxicity in Huntington's disease models.
Hegde RN et al.
The Embo Journal, 2020
Phosphorylation of huntingtin at residue T3 is decreased in Huntington's disease and modulates mutant huntingtin protein conformation.
Cariulo C et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017
Essential sequence of the N-terminal cytoplasmic localization-related domain of huntingtin and its effect on huntingtin aggregates.
Yan Y et al.
Science China. Life Sciences, 2011
Phosphorylation of threonine 3: implications for Huntingtin aggregation and neurotoxicity.
Aiken CT et al.
The Journal of Biological Chemistry, 2009
Select a paper to view details