Associated Papers
Mitophagy in the pathogenesis and management of disease.
Wang Q et al.
Cell Research, 2026
Protein aggregation in neurodegenerative diseases.
Wang J et al.
Chinese Medical Journal, 2025
G6PD deficiency triggers dopamine loss and the initiation of Parkinson's disease pathogenesis.
Stykel MG et al.
Cell Reports, 2025
Mechanism and Clinical Application Prospects of Mitochondrial DNA Single Nucleotide Polymorphism in Neurodegenerative Diseases.
Xu M et al.
Neurochemical Research, 2024
Targeting Protein Misfolding and Aggregation as a Therapeutic Perspective in Neurodegenerative Disorders.
Sidoryk-Węgrzynowicz M et al.
International Journal of Molecular Sciences, 2024
TOLLIP acts as a cargo adaptor to promote lysosomal degradation of aberrant ER membrane proteins.
Hayashi Y et al.
The Embo Journal, 2023
Effects of Mutations and Post-Translational Modifications on α-Synuclein In Vitro Aggregation.
Pancoe SX et al.
Journal of Molecular Biology, 2022
Protein Misfolding and Aggregation: The Relatedness between Parkinson's Disease and Hepatic Endoplasmic Reticulum Storage Disorders.
Padilla-Godínez FJ et al.
International Journal of Molecular Sciences, 2021
Treating Parkinson's Disease with Antibodies: Previous Studies and Future Directions.
Castonguay AM et al.
Journal of Parkinson's Disease, 2021
Targeting of Lysosomal Pathway Genes for Parkinson's Disease Modification: Insights From Cellular and Animal Models.
Abe T et al.
Frontiers in Neurology, 2021
Alpha-synuclein at the intracellular and the extracellular side: functional and dysfunctional implications.
Ottolini D et al.
Biological Chemistry, 2017
Hederagenin and α-hederin promote degradation of proteins in neurodegenerative diseases and improve motor deficits in MPTP-mice.
Wu AG et al.
Pharmacological Research, 2017
Autophagy and Alpha-Synuclein: Relevance to Parkinson's Disease and Related Synucleopathies.
Xilouri M et al.
Movement Disorders : Official Journal of the Movement Disorder Society, 2016
Familial Parkinson disease-associated mutations alter the site-specific microenvironment and dynamics of α-synuclein.
Sahay S et al.
The Journal of Biological Chemistry, 2015
Neferine attenuates the protein level and toxicity of mutant huntingtin in PC-12 cells via induction of autophagy.
Wong VK et al.
Molecules (basel, Switzerland), 2015
Macroautophagy in sporadic and the genetic form of Parkinson's disease with the A53T α-synuclein mutation.
Huang Y et al.
Translational Neurodegeneration, 2012
Common features at the start of the neurodegeneration cascade.
Hervás R et al.
Plos Biology, 2012
Inhibition of α-synuclein aggregation by small heat shock proteins.
Bruinsma IB et al.
Proteins, 2011
Genetic LRRK2 models of Parkinson's disease: Dissecting the pathogenic pathway and exploring clinical applications.
Yue Z et al.
Movement Disorders : Official Journal of the Movement Disorder Society, 2011
Alpha-synuclein targets the plasma membrane via the secretory pathway and induces toxicity in yeast.
Dixon C et al.
Genetics, 2005
Pathogenic effects of alpha-synuclein aggregation.
Lundvig D et al.
Brain Research. Molecular Brain Research, 2005