Varaico: Literature-Extracted Genetic Variants

Gene:HUWE1
Variant:p.K48R
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HUWE1

NM_031407.7:p.K48R

Associated Papers

Convergence of orphan quality control pathways at a ubiquitin chain-elongating ligase.

Carrillo Roas S et al.

Molecular Cell, 2025

39879985 (PubMed )
Supplement: EMS206527-supplement-Document_S2__Article_plus_supplemental_information__.pdf

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.

Waltho A et al.

Life Science Alliance, 2024

K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy.

Wang YT et al.

Cell Reports, 2022

Hepatitis B Core Protein Is Post-Translationally Modified through K29-Linked Ubiquitination.

Langerová H et al.

Cells, 2020

Histone demethylase JMJD1A promotes expression of DNA repair factors and radio-resistance of prostate cancer cells.

Fan L et al.

Cell Death & Disease, 2020

Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control.

Yau RG et al.

Cell, 2017

Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling.

Michel MA et al.

Molecular Cell, 2017

The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation.

Adhikary S et al.

Cell, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."