Varaico: Literature-Extracted Genetic Variants

Gene:HVCN1
Variant:p.D185A
Back to variants list

HVCN1

NM_032369.4:p.D185A

Associated Papers

Dimerization is required for the glycosylation of S1-S2 linker of sea urchin voltage-gated proton channel Hv1.

Okochi Y et al.

Biophysical Journal, 2024

Quantitative insights into the mechanism of proton conduction and selectivity for the human voltage-gated proton channel Hv1.

Liu Y et al.

Proceedings of the National Academy of Sciences of the United States of America, 2024

Role of the Voltage-Gated Proton Channel Hv1 in Nervous Systems.

Shen Y et al.

Neuroscience Bulletin, 2023

A novel Hv1 inhibitor reveals a new mechanism of inhibition of a voltage-sensing domain.

Zhao C et al.

The Journal of General Physiology, 2021

Coupling between an electrostatic network and the Zn2+ binding site modulates Hv1 activation.

De La Rosa V et al.

The Journal of General Physiology, 2018

Proton currents constrain structural models of voltage sensor activation.

Randolph AL et al.

Elife, 2016

Insights into the structure and function of HV1 from a meta-analysis of mutation studies.

DeCoursey TE et al.

The Journal of General Physiology, 2016

Aspartate 112 is the selectivity filter of the human voltage-gated proton channel.

Musset B et al.

Nature, 2011

22020278 (PubMed )
Supplement: NIHMS324797-supplement-1.pdf

Portability of paddle motif function and pharmacology in voltage sensors.

Alabi AA et al.

Nature, 2007

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."