Varaico: Literature-Extracted Genetic Variants

Gene:HVCN1
Variant:p.D112E
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HVCN1

NM_032369.4:p.D112E

Associated Papers

Quantitative insights into the mechanism of proton conduction and selectivity for the human voltage-gated proton channel Hv1.

Liu Y et al.

Proceedings of the National Academy of Sciences of the United States of America, 2024

The role of Phe150 in human voltage-gated proton channel.

Wu X et al.

Iscience, 2022

36388967 (PubMed )
Supplement: mmc1.pdf

Voltage-gated proton channels in polyneopteran insects.

Chaves G et al.

Febs Open Bio, 2022

A novel Hv1 inhibitor reveals a new mechanism of inhibition of a voltage-sensing domain.

Zhao C et al.

The Journal of General Physiology, 2021

Proton currents constrain structural models of voltage sensor activation.

Randolph AL et al.

Elife, 2016

Insights into the structure and function of HV1 from a meta-analysis of mutation studies.

DeCoursey TE et al.

The Journal of General Physiology, 2016

Interrogation of the intersubunit interface of the open Hv1 proton channel with a probe of allosteric coupling.

Hong L et al.

Scientific Reports, 2015

Voltage-gated proton channels: molecular biology, physiology, and pathophysiology of the H(V) family.

DeCoursey TE

Physiological Reviews, 2013

The pore of the voltage-gated proton channel.

Berger TK et al.

Neuron, 2011

Aspartate 112 is the selectivity filter of the human voltage-gated proton channel.

Musset B et al.

Nature, 2011

22020278 (PubMed )
Supplement: NIHMS324797-supplement-1.pdf
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