Varaico: Literature-Extracted Genetic Variants

Gene:HVCN1
Variant:p.D112N
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HVCN1

NM_032369.4:p.D112N

Associated Papers

Quantitative insights into the mechanism of proton conduction and selectivity for the human voltage-gated proton channel Hv1.

Liu Y et al.

Proceedings of the National Academy of Sciences of the United States of America, 2024

Trapping Charge Mechanism in Hv1 Channels (CiHv1).

Fernández M et al.

International Journal of Molecular Sciences, 2023

Coupling between an electrostatic network and the Zn2+ binding site modulates Hv1 activation.

De La Rosa V et al.

The Journal of General Physiology, 2018

Proton currents constrain structural models of voltage sensor activation.

Randolph AL et al.

Elife, 2016

Insights into the structure and function of HV1 from a meta-analysis of mutation studies.

DeCoursey TE et al.

The Journal of General Physiology, 2016

Aspartate 112 is the selectivity filter of the human voltage-gated proton channel.

Musset B et al.

Nature, 2011

22020278 (PubMed )
Supplement: NIHMS324797-supplement-1.pdf
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