Varaico: Literature-Extracted Genetic Variants

Gene:IARS1
Variant:p.P12A
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IARS1

NM_002161.6:p.P12A

Associated Papers

Mistranslating the genetic code with leucine in yeast and mammalian cells.

Davey-Young J et al.

Rna Biology, 2024

Influence of peroxisome proliferator-activated receptor-γ exon 2 and exon 6 and insulin receptor substrate (IRS)-1 Gly972Arg polymorphisms on insulin resistance and beta-cell function in southern mediterranean women with polycystic ovary syndrome.

Giandalia A et al.

Journal of Clinical & Translational Endocrinology, 2018

Genetic variation in TNFα, PPARγ, and IRS-1 genes, and their association with breast-cancer survival in the HEAL cohort.

Duggan C et al.

Breast Cancer Research and Treatment, 2018

Association between Genetic Variants and Diabetes Mellitus in Iranian Populations: A Systematic Review of Observational Studies.

Khodaeian M et al.

Journal of Diabetes Research, 2015

The role of epistasis in the etiology of Polycystic Ovary Syndrome among Indian women: SNP-SNP and SNP-environment interactions.

Dasgupta S et al.

Annals of Human Genetics, 2013

Peroxisome proliferator activated receptor gamma gene variants influence susceptibility and insulin related traits in Indian women with polycystic ovary syndrome.

Shaikh N et al.

Journal of Assisted Reproduction and Genetics, 2013

Genetic variants associated with insulin signaling and glucose homeostasis in the pathogenesis of insulin resistance in polycystic ovary syndrome: a systematic review.

Lakkakula BV et al.

Journal of Assisted Reproduction and Genetics, 2013

Polymorphisms in the IRS-1 and PPAR-γ genes and their association with polycystic ovary syndrome among South Indian women.

Dasgupta S et al.

Gene, 2012

The ENPP1 K121Q polymorphism is not associated with type 2 diabetes in northern Chinese.

Shi X et al.

Acta Diabetologica, 2011

The rs1801278 G>A polymorphism of IRS-1 is associated with metabolic syndrome in healthy nondiabetic men. Modulation by cigarette smoking status.

Pérez MS et al.

Diabetes Research and Clinical Practice, 2011

Single-nucleotide polymorphisms in peroxisome proliferator-activated receptor gamma and their association with plasma levels of resistin and the metabolic syndrome in a South Indian population.

Haseeb A et al.

Journal of Biosciences, 2009

Association testing of common variants in the insulin receptor substrate-1 gene (IRS1) with type 2 diabetes.

Florez JC et al.

Diabetologia, 2007

Common polymorphisms in the PPARgamma2 and IRS-1 genes and their interaction influence serum adiponectin concentration in young Finnish men.

Mousavinasab F et al.

Molecular Genetics and Metabolism, 2005

The insulin receptor substrate-1 Gly972Arg polymorphism is not associated with Type 2 diabetes mellitus in two population-based studies.

van Dam RM et al.

Diabetic Medicine : a Journal of the British Diabetic Association, 2004

The Arg972 variant in insulin receptor substrate-1 is associated with an increased risk of secondary failure to sulfonylurea in patients with type 2 diabetes.

Sesti G et al.

Diabetes Care, 2004

Evidence for genetic epistasis in human insulin resistance: the combined effect of PC-1 (K121Q) and PPARgamma2 (P12A) polymorphisms.

Baratta R et al.

Journal of Molecular Medicine (berlin, Germany), 2003

Perspective: the search for genes for type 2 diabetes in the post-genome era.

Elbein SC

Endocrinology, 2002

Interaction effect between common polymorphisms in PPARgamma2 (Pro12Ala) and insulin receptor substrate 1 (Gly972Arg) on insulin sensitivity.

Stumvoll M et al.

Journal of Molecular Medicine (berlin, Germany), 2002

The Gly972Arg polymorphism in the insulin receptor substrate-1 gene contributes to the variation in insulin secretion in normal glucose-tolerant humans.

Stumvoll M et al.

Diabetes, 2001

The role of PPARgamma in high-fat diet-induced obesity and insulin resistance.

Kadowaki T et al.

Journal of Diabetes and Its Complications, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."