Associated Papers
Substrate-selective inhibitors that reprogram the activity of insulin-degrading enzyme.
Maianti JP et al.
Nature Chemical Biology, 2019
31086331 (PubMed )
Supplement: NIHMS1524085-supplement-Supp_Info.pdf
Cysteine 904 is required for maximal insulin degrading enzyme activity and polyanion activation.
Song ES et al.
Plos One, 2012
Molecular bases for the recognition of short peptide substrates and cysteine-directed modifications of human insulin-degrading enzyme.
Malito E et al.
Biochemistry, 2008
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