Varaico: Literature-Extracted Genetic Variants

Gene:IDH1
Variant:p.K212Q
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IDH1

NM_005896.4:p.K212Q

Associated Papers

Oncometabolite D-2-Hydroxyglutarate Inhibits ALKBH DNA Repair Enzymes and Sensitizes IDH Mutant Cells to Alkylating Agents.

Wang P et al.

Cell Reports, 2015

NADP(+)-IDH Mutations Promote Hypersuccinylation that Impairs Mitochondria Respiration and Induces Apoptosis Resistance.

Li F et al.

Molecular Cell, 2015

Mutant IDH1 enhances the production of 2-hydroxyglutarate due to its kinetic mechanism.

Rendina AR et al.

Biochemistry, 2013

23731180 (PubMed )
Supplement: bi400514k_si_001.pdf
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."