Varaico: Literature-Extracted Genetic Variants

Gene:IDH1
Variant:p.Y135F
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IDH1

NM_005896.4:p.Y135F

Associated Papers

Mutant and Wild-Type Isocitrate Dehydrogenase 1 Share Enhancing Mechanisms Involving Distinct Tyrosine Kinase Cascades in Cancer.

Chen D et al.

Cancer Discovery, 2019

Prognostic implications and molecular associations of NADH dehydrogenase subunit 4 (ND4) mutations in acute myeloid leukemia.

Damm F et al.

Leukemia, 2012

Each conserved active site tyr in the three subunits of human isocitrate dehydrogenase has a different function.

Dange M et al.

The Journal of Biological Chemistry, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."