Varaico: Literature-Extracted Genetic Variants

Gene:IDH1
Variant:p.H133Q
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IDH1

NM_005896.4:p.H133Q

Associated Papers

Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Asselta R et al.

Thoracic Cancer, 2021

33704917 (PubMed )
Supplement: TCA-12-1271-s003.xls › Foglio1

Conventional chondrosarcoma with focal clear cell change: a clinicopathological and molecular analysis.

Lam SW et al.

Histopathology, 2019

Molecular Alterations in Thyroid Cancer: From Bench to Clinical Practice.

Tirrò E et al.

Genes, 2019

Prevalence of the single-nucleotide polymorphism rs11554137 (IDH1105GGT) in brain tumors of a cohort of Italian patients.

Acquaviva G et al.

Scientific Reports, 2018

Molecular mechanisms of isocitrate dehydrogenase 1 (IDH1) mutations identified in tumors: The role of size and hydrophobicity at residue 132 on catalytic efficiency.

Avellaneda Matteo D et al.

The Journal of Biological Chemistry, 2017

IDH1/2 mutations target a key hallmark of cancer by deregulating cellular metabolism in glioma.

Zhang C et al.

Neuro-oncology, 2013

Glioblastoma with oligodendroglial component represents a subgroup of glioblastoma with high prevalence of IDH1 mutation and association with younger age.

Ha SY et al.

Journal of Neuro-oncology, 2013

IDH1 and IDH2 mutations in tumorigenesis: mechanistic insights and clinical perspectives.

Yang H et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2012

Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production.

Ward PS et al.

Oncogene, 2012

Identification of several novel non-p.R132 IDH1 variants in thyroid carcinomas.

Hemerly JP et al.

European Journal of Endocrinology, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."